Chemical Composition and Platelet Aggregation Activity of Essential Oils of Two Species of the Genus Ocotea (Lauraceae)

被引：9
|
作者：
de Lima Yamaguchi, Klenicy Kazumy [1 ]
Alcantara, Joelma Moreira [1 ]
Lima, Emerson Silva [2 ]
da Veiga-Junior, Valdir Florencio [1 ]
机构：
[1] Univ Fed Amazonas, Dept Quim, Inst Ciencias Exatas, BR-69077040 Manaus, Amazonas, Brazil
[2] Univ Fed Amazonas, Fac Ciencias Farmaceut, BR-69010300 Manaus, Amazonas, Brazil
来源：
JOURNAL OF ESSENTIAL OIL BEARING PLANTS | 2013年 / 16卷 / 04期
关键词：
Ocotea; essential oils; platelet aggregation; beta-caryophyllene; ANTIPLATELET;
D O I：
10.1080/0972060X.2013.855364
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Essential oils from the leaves of Ocotea nigrescens Vicentini and Ocotea splendens (Meisn.) Baill collected in Manaus, Amazonas-Brazil, were obtained by hydrodistillation, analyzed by GC-FID and GC-MS, and evaluated for platelet aggregation. A total of 33 constituents were identified in the essential oils of these two species. beta-caryophyllene was the substance with the highest percentage in both Ocotea nigrescens (37.9 %) and Ocotea splendens (51.0 %). Other components detected were a-pinene (6.7 %), beta-pinene (6.9 %), linalool (5.5 %) and alpha-copaene (6.2 %), in Ocotea nigrescens; and caryophyllene oxide (9.9 %), linalool isovalerate (5.7 %), alpha-humulene (6.2 %) and a-guaiene (4.5 %) in Ocotea splendens. The essential oils of both species showed a low anti aggregant factor with 10.8 % for Ocotea nigrescens and 11.74 % for Ocotea splendens, as compared with the positive standard acetylsalicylic acid which strongly inhibits platelet aggregation (100 %).
引用
收藏
页码：518 / 523
页数：6
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