Regulatory T cells protect the brain after stroke

被引:31
|
作者
Planas, Anna M. [1 ]
Chamorro, Angel [2 ]
机构
[1] CSIC, Dept Brain Ischemia & Neurodegenerat, Inst Biomed Res Barcelona, Inst Invest Biomed August Pi & Sunyer, Barcelona 08036, Spain
[2] Univ Barcelona, Comprehens Stroke Ctr, Hosp Clin, Inst Invest Biomed August Pi & Sunyer, E-08036 Barcelona, Spain
关键词
ACUTE ISCHEMIC-STROKE; VASCULAR-DISEASE; SYSTEM;
D O I
10.1038/nm0209-138
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The inflammatory response goes haywire after stroke, and the brain floods with immune mediators that can injure tissue and worsen outcome. Experiments in mice suggest that regulatory T cells help contain the damage (pages 192–199).
引用
收藏
页码:138 / 139
页数:3
相关论文
共 50 条
  • [31] PRO: Regulatory T Cells Are Protective in Ischemic Stroke
    Hu, Xiaoming
    Li, Peiying
    Chen, Jun
    STROKE, 2013, 44 (08) : E85 - E86
  • [32] Immunotherapy as a treatment for Stroke: Utilizing regulatory T cells
    Li, Yuanwei
    Mcbride, Devin W.
    Tang, Yingxin
    Doycheva, Desislava
    Zhang, John H.
    Tang, Zhouping
    BRAIN HEMORRHAGES, 2023, 4 (03): : 147 - 153
  • [33] The Paradox Role of Regulatory T Cells in Ischemic Stroke
    Xu, Xiaomeng
    Li, Min
    Jiang, Yongjun
    SCIENTIFIC WORLD JOURNAL, 2013,
  • [34] Regulatory T Cells in Ischemic Stroke Helpful or Hazardous?
    Schaebitz, Wolf-Ruediger
    STROKE, 2013, 44 (08) : E84 - E84
  • [35] Regulatory T cells protect from autoimmune arthritis during pregnancy
    Munoz-Suano, Alba
    Kallikourdis, Marinos
    Sarris, Milka
    Betz, Alexander G.
    JOURNAL OF AUTOIMMUNITY, 2012, 38 (2-3) : J103 - J108
  • [36] The role of brain regulatory T cells during the chronic phase after CNS injury
    Ito, M.
    Yoshimura, A.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2019, 39 : 517 - 517
  • [37] Ischemic postconditioning as a novel avenue to protect against brain injury after stroke
    Zhao, Heng
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2009, 29 (05): : 873 - 885
  • [38] Regulatory T cells participate in the recovery of ischemic stroke patients
    Santamaria-Cadavid, Maria
    Rodriguez-Castro, Emilio
    Rodriguez-Yanez, Manuel
    Arias-Rivas, Susana
    Lopez-Dequidt, Iria
    Perez-Mato, Maria
    Rodriguez-Perez, Manuel
    Lopez-Loureiro, Ignacio
    Hervella, Pablo
    Campos, Francisco
    Castillo, Jose
    Iglesias-Rey, Ramon
    Sobrino, Tomas
    BMC NEUROLOGY, 2020, 20 (01)
  • [39] Regulatory T Cells in Post-stroke Immune Homeostasis
    Arthur Liesz
    Christoph Kleinschnitz
    Translational Stroke Research, 2016, 7 : 313 - 321
  • [40] Response of regulatory T cells to classic heat stroke in mice
    Hu, Jie
    Kang, Hong-Jun
    Liu, Chao
    Hu, Pan
    Yang, Meng-Meng
    Zhou, Fei-Hu
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 16 (06) : 4609 - 4615