Oncogenesis by E2A-PBX1 in ALL: RUNX and more

被引：6

作者：

Licht, Jonathan D. ^{[1
]}

机构：

[1] Univ Florida, Gainesville, FL 32611 USA

来源：

BLOOD | 2020年 / 136卷 / 01期

关键词：

PBX1;

D O I：

10.1182/blood.2020005879

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The mechanisms by which fusion transcription factors stimulate cancer pathogenesis are being elucidated with increasingly powerful molecular techniques. In this issue of Blood, Pi et al(1) performed a genome-wide identification of the targets of the E2A-PBX1 fusion protein associated with t(1;19), found in 4% of cases of childhood B-cell acute lymphocytic leukemia (ALL).

引用

页码：3 / 4

页数：2

共 50 条

[21] The advances of E2A-PBX1 fusion in B-cell acute lymphoblastic Leukaemia
Yang, Mengting
Tang, Yanhui
Zhu, Peng
Lu, Haiquan
Wan, Xiaohong
Guo, Qulian
Xiao, Lan
Liu, Chunyan
Guo, Ling
Liu, Wenjun
Yang, You
ANNALS OF HEMATOLOGY, 2024, 103 (09) : 3385 - 3398
[22] Comparative genomics reveals multistep pathogenesis of E2A-PBX1 acute lymphoblastic leukemia
Duque-Afonso, Jesus
Feng, Jue
Scherer, Florian
Lin, Chiou-Hong
Wong, Stephen H. K.
Wang, Zhong
Iwasaki, Masayuki
Cleary, Michael L.
JOURNAL OF CLINICAL INVESTIGATION, 2015, 125 (09): : 3667 - 3680
[23] The chimeric oncoproteins E2A-PBX1 and E2A-HLF are concentrated within spherical nuclear domains
D P LeBrun
B P Matthews
B J Feldman
M L Cleary
Oncogene, 1997, 15 : 2059 - 2067
[24] The chimeric oncoproteins E2A-PBX1 and E2A-HLF are concentrated within spherical nuclear domains
LeBrun, DP
Matthews, BP
Feldman, BJ
Cleary, ML
ONCOGENE, 1997, 15 (17) : 2059 - 2067
[25] siRNA-inhibition of E2A-PBX1 in pre-B leukemia cells
Casagrande, Giovanna
Te Kronnie, Geertruy
Basso, Giuseppe
INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 2007, 29 : 48 - 49
[26] E2A-PBX1 exhibited a promising prognosis in pediatric acute lymphoblastic leukemia treated with the CCLG-ALL2008 protocol
Hu, Yixin
He, Hailong
Lu, Jun
Wang, Yi
Xiao, Peifang
Li, Jianqin
Li, Jie
Sun, Yina
Lv, Hui
Fan, Junjie
Yao, Yanhua
Chai, Yihuan
Hu, Shaoyan
ONCOTARGETS AND THERAPY, 2016, 9 : 7219 - 7225
[27] E2A-PBX1 fusion in adult acute lymphoblastic leukaemia: biological and clinical features
Foa, R
Vitale, A
Mancini, M
Cuneo, A
Mecucci, C
Elia, L
Lombardo, R
Saglio, G
Torelli, G
Annino, L
Specchia, G
Damasio, E
Recchia, A
Di Raimondo, F
Morra, E
Volpe, E
Tafuri, A
Fazi, P
Hunger, SP
Mandelli, F
BRITISH JOURNAL OF HAEMATOLOGY, 2003, 120 (03) : 484 - 487
[28] Evidence for Hox and E2A-PBX1 collaboration in mouse T-cell leukemia
Bijl, J.
Krosl, J.
Lebert-Ghali, C-E
Vacher, J.
Mayotte, N.
Sauvageau, G.
ONCOGENE, 2008, 27 (49) : 6356 - 6364
[29] Pim1 cooperates with E2a-Pbx1 to facilitate the progression of thymic lymphomas in transgenic mice
Brian J Feldman
Tony R Reid
Michael L Cleary
Oncogene, 1997, 15 : 2735 - 2742
[30] Monoclonal antibodies specific to the fusion region of E2A-pbx1 chimeric protein in t(1;19) ALL: Characterization and diagnostic utility.
Sang, BC
Dias, P
Shi, L
Liu, L
Wei, J
Wang, ZX
Behm, F
Monell, CR
Singh, S
Huang, ECM
Wormsley, SB
Gruenwald, S
BLOOD, 1996, 88 (10) : 283 - 283

← 1 2 3 4 5 →