Bupropion-Associated QRS Prolongation Unresponsive to Sodium Bicarbonate Therapy

被引：12
|
作者：
Wills, Brandon K. [2 ]
Zell-Kanter, Michele [1 ,2 ]
Aks, Steven E. [3 ]
机构：
[1] Cook Cty Hosp, Sect Clin Toxicol, TOXIKON Consortium, Chicago, IL 60612 USA
[2] Madigan Army Med Ctr, Dept Emergency Med, Tacoma, WA 98431 USA
[3] Cook Cty Hosp, Dept Emergency Med, TOXIKON Consortium, Chicago, IL 60612 USA
来源：
AMERICAN JOURNAL OF THERAPEUTICS | 2009年 / 16卷 / 02期
关键词：
bupropion; overdose; QRS prolongation; sodium bicarbonate; OVERDOSE;
D O I：
10.1097/MJT.0b013e3180a5bd83
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
We describe a case of bupropion-associated QRS prolongation that was unresponsive to intravenous bolus therapy of sodium bicarbonate. Bupropion may cause seizures and conduction delays similar to tricyclic antidepressants in the overdose setting by an unknown mechanism.
引用
收藏
页码：193 / 196
页数：4
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