Relapse of chronic phase chronic myeloid leukemia (CML) on imatinib: BCR-ABL kinase domain mutations conferring drug resistance are frequently detectable prior to clinical evidence of relapse.

被引：0
|
作者：
Shah, NP [1 ]
Nicoll, JM [1 ]
Paquette, RL [1 ]
Sawyers, CL [1 ]
机构：
[1] Univ Calif Los Angeles, Jonsson Comprehens Canc Ctr, David Geffen Sch Med, Dept Med,Div Hematol Oncol, Los Angeles, CA 90024 USA
来源：
BLOOD | 2002年 / 100卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
1418
引用
收藏
页码：366A / 366A
页数：1
相关论文
共 50 条
  • [31] Increase of BCR-ABL/ABL Ratio That Corresponds to BCR-ABL Mutation Detection In Chronic Myeloid Leukemia (CML) Patients Treated by Imatinib (IM)
    Tsaur, Grigory
    Popov, Alexander
    Ivanova, Anna
    Yakovleva, Yulia
    Riger, Tatyana
    Plekhanova, Olga
    Ivanets, Yulia
    Shorikov, Egor
    Saveliev, Leonid
    Fechina, Larisa
    FASEB JOURNAL, 2011, 25
  • [32] Primary imatinib resistance in chronic myeloid leukaemia patients: a critical analysis of BCR-ABL kinase domain mutations and clinical outcomes in a developing country
    Yap, E.
    Tumian, N. R.
    Elias, M. H.
    Azma, R. Z.
    Sharifah, N. A.
    Salwati, S.
    Hamidah, N. H.
    Fadilah, S. A. W.
    Wong, C. L.
    BRITISH JOURNAL OF HAEMATOLOGY, 2015, 169 : 76 - 76
  • [33] SCREENING OF EXON 6 BCR-ABL KINASE DOMAIN MUTATIONS IN CHRONIC MYELOID LEUKEMIA (CML) PATIENTS TREATED WITH KINASE INHIBITORS USING DHPLC
    De Souza, C. A.
    Mascarenhas, C.
    Cunha, A.
    Pagnano, K.
    Silveira, R.
    Costa, F.
    Pasquini, R.
    Clementino, N.
    De Souza, C.
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2008, 93 : 540 - 540
  • [34] BCR-ABL kinase domain mutations, including 2 novel mutations in imatinib resistant Malaysian chronic myeloid leukemia patients-Frequency and clinical outcome
    Elias, Marjanu Hikmah
    Baba, Abdul Aziz
    Azlan, Husin
    Rosline, Hassan
    Sim, Goh Ai
    Padmini, Menon
    Fadilah, S. Abdul Wahid
    Ankathil, Ravindran
    LEUKEMIA RESEARCH, 2014, 38 (04) : 454 - 459
  • [35] The role of serial BCR-ABL transcript monitoring in predicting the emergence of BCR-ABL kinase mutations in imatinib-treated patients with chronic myeloid leukemia
    Wang, LH
    Knight, K
    Lucas, C
    Clark, RE
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2006, 91 (02): : 235 - 239
  • [36] Presence of a new BCR-ABL kinase domain mutation, C330G in an imatinib naive patient with chronic myeloid leukemia: very low prevalence of BCR-ABL kinase domain mutations in patients with chronic myeloid leukemia from eastern India
    Kuila, Nivedita
    Dash, Nilima
    Sahoo, Devi Prasad
    Pattnayak, Naresh Chandra
    Biswas, Ghanashyam
    Chakraborty, Soumen
    LEUKEMIA & LYMPHOMA, 2009, 50 (04) : 663 - 666
  • [37] BCR-ABL SH3-SH2 domain mutations in chronic myeloid leukemia patients on imatinib
    Sherbenou, Daniel W.
    Hantschel, Oliver
    Kaupe, Ines
    Willis, Stephanie
    Bumm, Thomas
    Turaga, Lalita P.
    Lange, Thoralf
    Dao, Kim-Hien
    Press, Richard D.
    Druker, Brian J.
    Superti-Furga, Giulio
    Deininger, Michael W.
    BLOOD, 2010, 116 (17) : 3278 - 3285
  • [38] ANALYSIS OF BCR-ABL KINASE DOMAIN MUTATIONS IN HUNGARIAN PATIENTS WITH IMATINIB RESISTANT CHRONIC MYELOID LEUKEMIA AND PHILADELPHIA POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA
    Meggyesi, N.
    Bors, A.
    Halm, G.
    Nahajevszky, S.
    Barta, A.
    Lueff, S.
    Batai, A.
    Remenyi, P.
    Masszi, T.
    Fekete, S.
    Ujj, G.
    Tordai, A.
    Andrikovics, H.
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 : 538 - 538
  • [39] BCR-ABL duplication revealed by fish analysis is frequently associated with imatinib resistance in chronic phase chronic myelogenous leukemia patients
    Rousselot, Ph.
    Mossafa, H.
    Joha, S.
    Tigaud, I.
    Rea, D.
    Corm, S.
    Hayette, S.
    Cayuela, J. M.
    Maarek, O.
    Roche-Lestienne, C.
    Terre, C.
    Lev, V.
    Preudhomme, C.
    Michallet, M.
    Calvo, F.
    Nicolini, F.
    Rousselot, P.
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2007, 92 : 356 - 357
  • [40] Induction of BCR-ABL mutations for acquired resistance in chronic myelogenous leukemia cells by imatinib
    Yuan, Hongfeng
    Gao, Chunggang
    Bhatia, Ravi
    Chen, WenYong
    CANCER RESEARCH, 2009, 69
12345