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Perioperative medical management of ischemic heart disease in patients undergoing noncardiac surgery
被引:8
|作者:
Feringa, Harm H. H.
[1
]
Bax, Jeroen J.
[1
]
Poldermans, Don
[2
]
机构:
[1] Leiden Univ, Med Ctr, Dept Cardiol, Leiden, Netherlands
[2] Erasmus MC, Dept Anesthesiol, Dr Molewaterpl 40, NL-3015 GD Rotterdam, Netherlands
关键词:
ischemic heart disease;
medical therapy;
noncardiac surgery;
risk stratification;
D O I:
10.1097/ACO.0b013e3280c60c50
中图分类号:
R614 [麻醉学];
学科分类号:
100217 ;
摘要:
Purpose of review Cardiovascular disease is the leading cause of death after anesthesia and surgery. The preoperative identification of patients with underlying coronary artery disease is important to initiate appropriate treatment strategies in order to reduce the risk of perioperative complications. The current review will discuss new insights in the field of perioperative medicine that can be applied to clinical practice or stimulate further investigation. Recent findings Recent findings in the past year have developed preoperative risk stratification in terms of simplicity, safety, accuracy and cost-effectiveness. Natriuretic peptides have been demonstrated to be promising new preoperative risk markers. Although recommended in high-risk patients, noninvasive cardiac stress testing may be safely omitted in patients at intermediate risk. The antiischemic properties of b-blockers have been well described. In clinical practice, however, adequate b-blocker dosage, tight perioperative heart rate control and continuation of b-blockers after surgery may also be important factors. Statins have emerged as promising drugs with perioperative cardioprotective properties. Before recommending routine administration of statin therapy, however, more clinical trials are needed. Summary New perceptions in perioperative medical management and novel developments in surgical and anesthesiology techniques continue to improve the cardiovascular outcome of patents undergoing major noncardiac surgery.
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页码:254 / 260
页数:7
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