Vitamin D Status in Migraine Patients: A Case-Control Study

被引：20
|
作者：
Zandifar, Alireza [1 ,2 ]
Masjedi, Samaneh Sadat [2 ]
Banihashemi, Mahboobeh [2 ]
Asgari, Fatemeh [2 ]
Manouchehri, Navid [2 ]
Ebrahimi, Homa [3 ]
Haghdoost, Faraidoon [1 ,2 ]
Saadatnia, Mohammad [1 ,4 ,5 ]
机构：
[1] Isfahan Univ Med Sci, Dept Physiol, Physiol Res Ctr, Esfahan 81745319, Iran
[2] Isfahan Univ Med Sci, Med Student Res Ctr, Esfahan 81745319, Iran
[3] Islamic Azad Univ, NajafAbad Branch, Med Student Res Ctr, Fac Med, Najafabad 8514143131, Iran
[4] Isfahan Univ Med Sci, Dept Neurol, Esfahan 81745319, Iran
[5] Isfahan Univ Med Sci, Isfahan Neurosci Res Ctr, Esfahan 81745319, Iran
来源：
BIOMED RESEARCH INTERNATIONAL | 2014年 / 2014卷
关键词：
D DEFICIENCY; PARATHYROID-HORMONE; 25-HYDROXYVITAMIN D; HEADACHE; PREVALENCE; ASSOCIATION; DYSFUNCTION; IMPACT; PAIN;
D O I：
10.1155/2014/514782
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Background. There have been few studies on the relation between vitamin D and migraine. We investigated the prevalence of vitamin D deficiency in migraine patients and compared it with a control group. We also evaluated the relationship of vitamin D deficiency with severity of migraine. Methods. 105 newly diagnosed migraine patients and 110 controls, matched for age, sex, socioeconomic status, education, and sun exposure, were enrolled during the spring of 2011. 25-Hydroxy vitamin D [25(OH)D] plasma levels were measured by chemiluminescence immunoassay. Results. The mean +/- SE concentration of 25(OH) D was 13.55 +/- 0.91 ng/mL in cases and 13.19 +/- 1.19 ng/mL in controls. There was no significant difference in 25(OH) D concentration between cases and controls. We found no relationship between severity of headache and 25(OH) D status. Conclusions. We did not find any association between migraine and vitamin D status; also, severity of headaches was not related to 25(OH) D level. Further studies with larger sample sizes are required to confirm our results.
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页数：7
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