Potential intracranial applications of magnetic resonance-guided focused ultrasound surgery

被引:69
|
作者
Monteith, Stephen [1 ]
Sheehan, Jason [1 ]
Medel, Ricky [1 ]
Wintermark, Max [2 ]
Eames, Matthew [3 ]
Snell, John [3 ]
Kassell, Neal F. [1 ,3 ]
Elias, W. Jeff [1 ]
机构
[1] Univ Virginia Hlth Syst, Dept Neurol Surg, Charlottesville, VA 22908 USA
[2] Univ Virginia Hlth Syst, Dept Neuroradiol, Charlottesville, VA 22908 USA
[3] Focused Ultrasound Fdn, Charlottesville, VA USA
关键词
magnetic resonance-guided focused ultrasound surgery; focused ultrasound; high-intensity focused ultrasound; GAMMA-KNIFE RADIOSURGERY; IDIOPATHIC TRIGEMINAL NEURALGIA; BLOOD-BRAIN-BARRIER; ENDOSCOPIC 3RD VENTRICULOSTOMY; TEMPORAL-LOBE EPILEPSY; IN-VITRO; STEREOTACTIC RADIOSURGERY; INITIAL-EXPERIENCE; THROMBOLYSIS; OUTCOMES;
D O I
10.3171/2012.10.JNS12449
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Magnetic resonance-guided focused ultrasound surgery (MRgFUS) has the potential to create a shift in the treatment paradigm of several intracranial disorders. High-resolution MRI guidance combined with an accurate method of delivering high doses of transcranial ultrasound energy to a discrete focal point has led to the exploration of noninvasive treatments for diseases traditionally treated by invasive surgical procedures. In this review, the authors examine the current intracranial applications under investigation and explore other potential uses for MRgFUS in the intracranial space based on their initial cadaveric studies. (http://thejns.org/doi/abs/10.3171/2012.10.JNS12449)
引用
收藏
页码:215 / 221
页数:7
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