Stereospecific synthesis of 2′-O-α-D-ribofuranosylnucleosides

被引：0

作者：

Kulikova, Irina V. ^{[1
]}

Muradova, Daria A. ^{[1
]}

Varizhuk, Ivan S. ^{[1
]}

Mikhailov, Sergey N. ^{[1
]}

机构：

[1] Russian Acad Sci, Engelhardt Inst Mol Biol, Moscow 119991, Russia

来源：

CHEMISTRY OF NUCLEIC ACID COMPONENTS | 2008年 / 10卷

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The first chemical synthesis of 2'-O-alpha-D-ribofuranosyluridine and 2'-O-alpha-D-ribofuranosyladenosine, monomeric unit of poly(ADP-ribose), has been achieved starting from 3',5'-O-bis protected 2'-O-alpha-D-arabinofuranosylnucleosides. Configurational inversion of 2'-hydroxyl group of arabinose moiety was performed by oxidation-reduction sequence.

引用

页码：155 / 158

页数：4

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