Differences in hair cortisol concentrations and reported anxiety in women with preeclampsia versus uncomplicated pregnancies

被引:8
|
作者
van Esch, Joris J. A. [1 ]
Bolte, Antoinette C. [1 ]
Vandenbussche, Frank P. H. A. [1 ]
Schippers, Daniela H. [2 ]
de Weerth, Carolina [3 ]
Beijers, Roseriet [4 ]
机构
[1] Radboud Univ Nijmegen, Med Ctr, Dept Obstet & Gynecol, POB 9101,Post 791, NL-6500 HB Nijmegen, Netherlands
[2] Canisius Wilhelmina Hosp, Dept Obstet & Gynecol, POB 9105, NL-6500 GS Nijmegen, Netherlands
[3] Radboud Univ Nijmegen, Med Ctr, Dept Cognit Neurosci, Donders Inst Brain Cognit & Behav, Kapittelweg 29, NL-6525 EN Nijmegen, Netherlands
[4] Radboud Univ Nijmegen, Dept Dev Psychol, Behav Sci Inst, POB 9104, NL-6500 HE Nijmegen, Netherlands
关键词
Early-onset preeclampsia; Late-onset preeclampsia; Psychosocial stress; Anxiety; Hair cortisol; PSYCHOSOCIAL STRESS; EARLY-ONSET; ASSOCIATION; HEALTH;
D O I
10.1016/j.preghy.2020.06.006
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
This Dutch multicenter case-controlled study investigated whether cortisol concentrations and psychosocial stress during pregnancy differed between women with early-onset preeclampsia, late-onset preeclampsia, and uncomplicated pregnancies. Cortisol concentrations were analyzed in three hair segments representing the preconception period, first, and second trimester of pregnancy. Cortisol trajectories differed, with early-onset preeclampsia showing steeper increases in cortisol and higher cortisol concentrations during the second trimester. Reported anxiety in women with preeclampsia was higher compared to women with uncomplicated pregnancies. These results indicate that measures of cortisol and reported anxiety differ between early-onset, late-onset preeclampsia, and uncomplicated pregnancies.
引用
收藏
页码:200 / 202
页数:3
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