Bone Metastases from Prostate Cancer 18F-Fluoride PET/CT in a Patient With Discordant Bone Scintigraphy and 11C-Choline PET/CT

Bone scintigraphy has been used extensively in prostate cancer patients to detect bone involvement. C-11-choline PET/CT is indicated when a biochemical recurrence is suspected, as this procedure is able to detect local recurrence, lymph-node infiltration, and metastases. In cases where the results of these 2 procedures do not coincide, MRI is then usually performed. F-18-fluoride may become an alternative to MRI for bone imaging In our patient series, all bone lesions with C-11-choline uptake were metastases. F-18-Fluoride did not increase specificity of C-11-choline but increased sensitivity of bone scintigraphy. CT helped in the interpretation of osteoarthritis and trauma lesions.