Protein phosphatase 2A promotes IL-2R signaling in human regulatory T cells

被引:0
|
作者
Ding, Ying [1 ]
Yu, Aixin [1 ]
Malek, Thomas R. [1 ]
机构
[1] Univ Miami, Miller Sch Med, Coral Gables, FL 33124 USA
来源
JOURNAL OF IMMUNOLOGY | 2018年 / 200卷 / 01期
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
176.10
引用
收藏
页数:2
相关论文
共 50 条
  • [41] IL-2Rα mediates temporal regulation of IL-2 signaling and enhances immunotherapy
    Su, Ee W.
    Moore, Caitlin J.
    Suriano, Samantha
    Johnson, Christopher Bryce
    Songalia, Neizel
    Patterson, Alicia
    Neitzke, Daniel J.
    Andrijauskaite, Kristina
    Garrett-Mayer, Elizabeth
    Mehrotra, Shikhar
    Paulos, Chrystal M.
    Doedens, Andrew L.
    Goldrath, Ananda W.
    Li, Zihai
    Cole, David J.
    Rubinstein, Mark P.
    SCIENCE TRANSLATIONAL MEDICINE, 2015, 7 (311)
  • [42] Prevention of Acute Graft-Versus-Host Disease Using an Engineered Mouse Orthogonal IL-2/IL-2Rß Regulatory T Cells
    Ramos, Teresa Lopes
    Wagers, Sara B.
    Lin, Po-Yu
    Hirai, Toshihito
    Su, Leon
    Picton, Lora
    Baker, Jeanette
    Lohmeyer, Juliane
    Mavers, Melissa
    Garcia, Christopher
    Blazar, Bruce R.
    Negrin, Robert S.
    BLOOD, 2021, 138
  • [43] CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rβ-deficient mice:: implications for the nonredundant function of IL-2
    Malek, TR
    Yu, AX
    Vincek, V
    Scibelli, P
    Kong, L
    IMMUNITY, 2002, 17 (02) : 167 - 178
  • [44] Protein phosphatase 2A: the Trojan Horse of cellular signaling
    Sontag, E
    CELLULAR SIGNALLING, 2001, 13 (01) : 7 - 16
  • [45] An NMDA receptor signaling complex with protein phosphatase 2A
    Chan, SF
    Sucher, NJ
    JOURNAL OF NEUROSCIENCE, 2001, 21 (20): : 7985 - 7992
  • [46] Homeostasis of peripheral CD4+ T cells:: IL-2Rα and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers
    Almeida, ARM
    Legrand, N
    Papiernik, M
    Freitas, AA
    JOURNAL OF IMMUNOLOGY, 2002, 169 (09): : 4850 - 4860
  • [47] Regulation of distinct IL-2R signaling pattern in CD4+CD25+regulatory T cells by the tumor suppressor gene PTEN.
    Walsh, PT
    Bensinger, SJ
    Zhang, JD
    Wang, J
    Dalton, N
    Turka, LA
    AMERICAN JOURNAL OF TRANSPLANTATION, 2004, 4 : 262 - 262
  • [48] Conserved IL-2Rγc Signaling Mediates Lymphopoiesis in Zebrafish
    Sertori, Robert
    Liongue, Clifford
    Basheer, Faiza
    Lewis, Kanako L.
    Rasighaemi, Parisa
    de Coninck, Dennis
    Traver, David
    Ward, Alister C.
    JOURNAL OF IMMUNOLOGY, 2016, 196 (01): : 135 - 143
  • [49] Immunological localization of the regulatory, structural and catalytic subunits of protein phosphatase 2A in pancreatic β cells
    Veluthakal, R
    Rengasamy, P
    Wadzinski, B
    Kowluru, A
    DIABETES, 2003, 52 : A385 - A385
  • [50] Essential and non-overlapping IL-2Rα-dependent processes for thymic development and peripheral homeostasis of regulatory T cells
    Toomer, Kevin H.
    Lui, Jen Bon
    Altman, Norman H.
    Ban, Yuguang
    Chen, Xi
    Malek, Thomas R.
    NATURE COMMUNICATIONS, 2019, 10 (1)