Co-activation of P2Y1 and P2TAC receptors and subsequent platelet aggregation are essential for ADP-induced thromboxane A2 generation in human platelets

被引:0
|
作者
Jin, J [1 ]
Kunapuli, SP [1 ]
机构
[1] Temple Univ, Sch Med, Philadelphia, PA 19140 USA
来源
FASEB JOURNAL | 1999年 / 13卷 / 07期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:A1512 / A1512
页数:1
相关论文
共 50 条
  • [41] Antipsychotic Drugs Inhibit Platelet Aggregation via P2Y1 and P2Y12 Receptors
    Wu, Chang-Chieh
    Tsai, Fu-Ming
    Chen, Mao-Liang
    Wu, Semon
    Lee, Ming-Cheng
    Tsai, Tzung-Chieh
    Wang, Lu-Kai
    Wang, Chun-Hua
    BIOMED RESEARCH INTERNATIONAL, 2016, 2016
  • [42] Conformational constraints of extracellular loop 2 are essential for activation of human P2Y1 receptors.
    Hoffmann, C
    Moro, S
    Nicholas, RA
    Harden, TK
    Jacobson, KA
    FASEB JOURNAL, 1998, 12 (08): : A1458 - A1458
  • [43] Differential involvement of the P2Y1 and P2YT receptors in the morphological changes of platelet aggregation
    Eckly, A
    Gendrault, JL
    Hechler, B
    Cazenave, JP
    Gachet, C
    THROMBOSIS AND HAEMOSTASIS, 2001, 85 (04) : 694 - 701
  • [44] Calmodulin interacts with the platelet ADP receptor P2Y1
    Arthur, Jane F.
    Shen, Yang
    Mu, Fi-Tjen
    Leon, Catherine
    Gachet, Christian
    Berndt, Michael C.
    Andrews, Robert K.
    BIOCHEMICAL JOURNAL, 2006, 398 (339-343) : 339 - 343
  • [45] Study of aggregation of platelets lacking the P2Y1 receptor
    Fabre, JE
    King, BF
    Koller, BH
    DRUG DEVELOPMENT RESEARCH, 2001, 52 (1-2) : 150 - 155
  • [46] ADP can induce aggregation of human platelets via both P2Yι and P2τ receptors
    Jarvis, GE
    Humphries, RG
    Robertson, MJ
    Leff, P
    BRITISH JOURNAL OF PHARMACOLOGY, 1998, 124 : U20 - U20
  • [47] Synergistic action between inhibition of P2Y12/P2Y1 and P2Y12/thrombin in ADP- and thrombin-induced human platelet activation
    Nylander, S
    Mattsson, C
    Ramström, S
    Lindahl, TL
    BRITISH JOURNAL OF PHARMACOLOGY, 2004, 142 (08) : 1325 - 1331
  • [48] Blockade of both ADP receptors, P2T and P2Y1, is necessary for effective inhibition of platelet aggregation under flow.
    Turner, NA
    Moake, JL
    Turner, JD
    McIntire, LV
    BLOOD, 1999, 94 (10) : 447A - 447A
  • [50] A small molecule inhibitor of P2Y1 blocks adp-induced aggregation but not shape change via an allosteric mechanism
    Mairuhu, R.
    LDowal
    Dilks, J. R.
    Blaira, P.
    Flaumenhaft, R.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2009, 7 : 661 - 661