Synthesis and characterization of new N-substituted 2-aminopyrrole derivatives

被引：5
|
作者：
Aksu, Kadir [1 ]
Ozgeris, Bunyamin [2 ]
Tumer, Ferhan [3 ]
机构：
[1] Ordu Univ, Chem Dept, Ordu, Turkey
[2] Erzurum Tech Univ, Basic Sci Dept, Erzurum, Turkey
[3] Kahramanmaras Sutcu Imam Univ, Chem Dept, TR-46100 Kahramanmaras, Turkey
来源：
ORGANIC COMMUNICATIONS | 2019年 / 12卷 / 01期
关键词：
Pyrrole; aminopyrrole; Knoevenagel condensation; Gewald reaction; PYRROLE;
D O I：
10.25135/acg.oc.55.19.03.1222
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In this work, new N-substituted 2-aminopyrrole derivatives were synthesized. Initially, some crotonitriles were prepared by condensation of malononitrile with arylmethylketones, which was followed by conversion of them to the bromocrotonitriles. Finally, the synthesis of new N-substituted 2-aminopyrrole derivates were successfully achieved by cyclization of the bromocrotonitriles of (R)-1-phenylethylamine applying Gewald method.
引用
收藏
页码：38 / 42
页数：5
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