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Writer's cramp
被引:13
|作者:
Goldman, Jennifer G.
[1
]
机构:
[1] Rush Univ, Med Ctr, Dept Neurol Sci, Sect Parkinson Dis & Movement Disorders, Chicago, IL 60612 USA
来源:
关键词:
Botulinum toxin;
Focal hand dystonia;
Mirror dystonia;
Occupational cramp;
Sensory trick;
Task-specific;
FOCAL HAND DYSTONIA;
TRANSCRANIAL MAGNETIC STIMULATION;
PRIMARY SOMATOSENSORY CORTEX;
PRIMARY WRITING TREMOR;
1-YEAR FOLLOW-UP;
BOTULINUM TOXIN;
MIRROR DYSTONIA;
GAG DELETION;
IMPROVES;
TASK;
D O I:
10.1016/j.toxicon.2015.09.024
中图分类号:
R9 [药学];
学科分类号:
1007 ;
摘要:
Writer's cramp is the most common form of focal, task-specific dystonia. Symptoms frequently evolve in the setting of repetitive hand movements and increased writing demands, and clinical presentations demonstrate a variety of different dystonic patterns of the upper extremity such as while writing or holding a writing utensil. However, why writer's cramp develops still remains much of a mystery. Clinical evaluation of patients with writer's cramp and various theories regarding its pathophysiology are reviewed. Treatment can be challenging and often involves a combination of pharmacologic (e.g., oral medications, botulinum toxin injections) and non-pharmacologic approaches (e.g., neurosurgical or neurostimulatory interventions, rehabilitation therapies, adaptive devices). Management strategies for writer's cramp using both of these approaches will be discussed. (C) 2015 Elsevier Ltd. All rights reserved.
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页码:98 / 104
页数:7
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