Immobilized artificial membrane (IAM) technology - A tool for predicting drug permeability through the blood-brain barrier

被引:0
|
作者
Reichel, A [1 ]
Begley, DJ [1 ]
Abbott, NJ [1 ]
机构
[1] UNIV LONDON KINGS COLL,DIV BIOMED SCI,DEPT PHYSIOL,LONDON WC2R 2LS,ENGLAND
来源
JOURNAL OF PHYSIOLOGY-LONDON | 1996年 / 491P卷
关键词
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:P30 / P30
页数:1
相关论文
共 50 条
  • [31] Advances in immobilized artificial membrane (IAM) chromatography for novel drug discovery
    Tsopelas, Fotios
    Vallianatou, Theodosia
    Tsantili-Kakoulidou, Anna
    EXPERT OPINION ON DRUG DISCOVERY, 2016, 11 (05) : 473 - 488
  • [32] Relationship between permeability status of the blood-brain barrier and in vitro permeability coefficient of a drug
    Gaillard, PJ
    de Boer, AG
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2000, 12 (02) : 95 - 102
  • [33] Rapid screening of blood-brain barrier penetration of drugs using the immobilized artificial membrane phosphatidylcholine column chromatography
    Yoon, CH
    Kim, SJ
    Soo, BS
    Lee, SC
    Yoo, SD
    JOURNAL OF BIOMOLECULAR SCREENING, 2006, 11 (01) : 13 - 20
  • [34] Predicting blood-brain barrier permeability of drugs:: Evaluation of different in vitro assays
    Lohmann, C
    Hüwel, S
    Galla, HJ
    JOURNAL OF DRUG TARGETING, 2002, 10 (04) : 263 - 276
  • [35] PERMEABILITY OF ANTIBIOTICS THROUGH BLOOD-BRAIN BARRIER IN PATIENTS WITH SUPPURATIVE MENINGITIS
    MOSIYCHU.NM
    SOVIET NEUROLOGY AND PSYCHIATRY-USSR, 1969, 2 (02): : 74 - +
  • [36] Predicting blood-brain barrier permeability of marine-derived kinase inhibitors
    Plisson, Fabien
    Piggott, Andrew
    Hamilton, Nicholas
    Capon, Robert
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256
  • [37] Development of a blood-brain barrier model in a membrane-based microchip for characterization of drug permeability and cytotoxicity for drug screening
    Shao, Xiaojian
    Gao, Dan
    Chen, Yongli
    Jin, Feng
    Hu, Guangnan
    Jiang, Yuyang
    Liu, Hongxia
    ANALYTICA CHIMICA ACTA, 2016, 934 : 186 - 193
  • [38] Evaluation of sphingomyelin, cholester, and phosphatidylcholine-based immobilized artificial membrane liquid chromatography to predict drug penetration across the blood-brain barrier
    Mike De Vrieze
    Dieter Verzele
    Roman Szucs
    Pat Sandra
    Frédéric Lynen
    Analytical and Bioanalytical Chemistry, 2014, 406 : 6179 - 6188
  • [39] Immobilized-artificial-membrane chromatography: Measurements of membrane partition coefficient and predicting drug membrane permeability
    Ong, SW
    Liu, HL
    Pidgeon, C
    JOURNAL OF CHROMATOGRAPHY A, 1996, 728 (1-2) : 113 - 128
  • [40] Evaluation of sphingomyelin, cholester, and phosphatidylcholine-based immobilized artificial membrane liquid chromatography to predict drug penetration across the blood-brain barrier
    De Vrieze, Mike
    Verzele, Dieter
    Szucs, Roman
    Sandra, Pat
    Lynen, Frederic
    ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2014, 406 (25) : 6179 - 6188