Novel antitussive strategies

被引：8
|
作者：
Morjaria, Jaymin B. [1 ]
Dickinson, Rebecca S. [1 ]
Morice, Alyn H. [1 ]
机构：
[1] Univ Hull, Hull York Med Sch, Castle Hill Hosp, Div Cardiovasc & Resp Studies, Cottingham HU16 5JQ, E Riding Yorksh, England
来源：
DRUG DISCOVERY TODAY | 2013年 / 18卷 / 7-8期
关键词：
CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES; RECEPTOR POTENTIAL VANILLOID-1; CHRONIC COUGH; LESOGABERAN AZD3355; GABA(B)-RECEPTOR AGONIST; SELECTIVE INHIBITORS; SENSORY NEUROPATHY; TREATABLE CAUSE; IN-VITRO; DEXTROMETHORPHAN;
D O I：
10.1016/j.drudis.2012.11.004
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Acute and chronic cough represent one of the most common symptoms of medical importance but effective pharmacotherapy is, to all intents and purposes, absent. Numerous initiatives targeting the recently discovered tussive pathways are in progress. Here, we review the current antitussive armamentarium and provide an update on the novel strategies and compounds in development.
引用
收藏
页码：380 / 388
页数：9
相关论文
共 50 条
  • [21] ANTITUSSIVE ACTIVITY OF ETHANOL
    CALESNICK, B
    VERNICK, H
    QUARTERLY JOURNAL OF STUDIES ON ALCOHOL, 1971, 32 (02): : 434 - 441
  • [22] PHENOBARBITAL: THE ULTIMATE ANTITUSSIVE
    Arian, Muhammad
    Stoever, Jonathan
    CHEST, 2023, 164 (04) : 1993A - 1993A
  • [23] Dependency Making Antitussive
    Cieslak, G.
    NERVENARZT, 1955, 26 (01): : 30 - 32
  • [24] Antitussive Activity of Anar
    O. I. Epstein
    V. L. Kovaleva
    M. S. Zak
    Bulletin of Experimental Biology and Medicine, 2003, 135 (Suppl 7) : 96 - 98
  • [25] EVALUATION OF AN ANTITUSSIVE DRUG
    GRUBER, CM
    SPARKMAN, DR
    EPSTEIN, IL
    CARTER, CH
    LARGAESPADA, M
    CHERNISH, SM
    RAFALSKI, TA
    KILLINGER, RR
    PRIEBE, F
    JOURNAL OF THE INDIANA STATE MEDICAL ASSOCIATION, 1961, 54 (11): : 1643 - +
  • [26] ANTITUSSIVE PROPERTIES OF BUTORPHANOL
    CAVANAGH, RL
    GYLYS, JA
    BIERWAGEN, ME
    ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE, 1976, 220 (02): : 258 - 268
  • [27] COMBINATION OF AN ANTITUSSIVE AND AN ANTISPASMODIC
    不详
    PRACTITIONER, 1967, 199 (1193) : 693 - &
  • [28] NEWER ANTITUSSIVE AGENTS
    BICKERMAN, H
    MEDICAL CLINICS OF NORTH AMERICA, 1961, 45 (04) : 805 - &
  • [29] ANTITUSSIVE ACTIVITY OF MEDAZONAMIDE
    MAFFII, G
    SILVESTR.B
    BANFI, S
    NATURE, 1965, 205 (4974) : 914 - &
  • [30] THE ANTITUSSIVE EFFECTS OF ACUPUNCTURE
    KOH, TC
    AMERICAN JOURNAL OF ACUPUNCTURE, 1983, 11 (02) : 163 - 164
12345