Novel antitussive strategies

被引：8

作者：

Morjaria, Jaymin B. ^{[1
]}

Dickinson, Rebecca S. ^{[1
]}

Morice, Alyn H. ^{[1
]}

机构：

[1] Univ Hull, Hull York Med Sch, Castle Hill Hosp, Div Cardiovasc & Resp Studies, Cottingham HU16 5JQ, E Riding Yorksh, England

来源：

DRUG DISCOVERY TODAY | 2013年 / 18卷 / 7-8期

关键词：

CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES; RECEPTOR POTENTIAL VANILLOID-1; CHRONIC COUGH; LESOGABERAN AZD3355; GABA(B)-RECEPTOR AGONIST; SELECTIVE INHIBITORS; SENSORY NEUROPATHY; TREATABLE CAUSE; IN-VITRO; DEXTROMETHORPHAN;

D O I：

10.1016/j.drudis.2012.11.004

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Acute and chronic cough represent one of the most common symptoms of medical importance but effective pharmacotherapy is, to all intents and purposes, absent. Numerous initiatives targeting the recently discovered tussive pathways are in progress. Here, we review the current antitussive armamentarium and provide an update on the novel strategies and compounds in development.

引用

页码：380 / 388

页数：9

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