TRP Channels

被引：129
|
作者：
Gees, Maarten [1 ,2 ]
Owsianik, Grzegorz [1 ,2 ]
Nilius, Bernd [1 ,2 ]
Voets, Thomas [1 ,2 ]
机构：
[1] Katholieke Univ Leuven, Lab Ion Channel Res, Louvain, Belgium
[2] Katholieke Univ Leuven, TRP Res Platform Leuven TRPLe, Louvain, Belgium
来源：
COMPREHENSIVE PHYSIOLOGY | 2012年 / 2卷 / 01期
关键词：
NONSELECTIVE CATION CHANNEL; POLYCYSTIC KIDNEY-DISEASE; EPITHELIAL CA2+ CHANNELS; RECEPTOR POTENTIAL CHANNELS; MUCOLIPIDOSIS TYPE-IV; INTEGRAL MEMBRANE-PROTEIN; MOUSE TRANSIENT RECEPTOR; ARTERIAL SMOOTH-MUSCLE; HEAT-EVOKED ACTIVATION; CALCIUM-ENTRY CHANNEL;
D O I：
10.1002/cphy.c110026
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
TRP channels constitute a large superfamily of cation channel forming proteins, all related to the gene product of the transient receptor potential (trp) locus in Drosophila. In mammals, 28 different TRP channel genes have been identified, which exhibit a large variety of functional properties and play diverse cellular and physiological roles. In this article, we provide a brief and systematic summary of expression, function, and (patho)physiological role of the mammalian TRP channels. (C) 2012 American Physiological Society. Compr Physiol 2: 563-608, 2012.
引用
收藏
页码：563 / 608
页数：46
相关论文
共 50 条
  • [31] TRP channels in mechanosensation
    Lin, SY
    Corey, DP
    CURRENT OPINION IN NEUROBIOLOGY, 2005, 15 (03) : 350 - 357
  • [32] TRP channels and thermosensation
    Patapoutian, A
    CHEMICAL SENSES, 2005, 30 : I193 - i194
  • [33] Organellar TRP channels
    Zhang, Xiaoli
    Hu, Meiqin
    Yang, Yexin
    Xu, Haoxing
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2018, 25 (11) : 1009 - 1018
  • [34] TRP channels in disease
    Nilius, Bernd
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2007, 1772 (08): : 805 - 812
  • [35] Trp channels and itch
    Sun, Shuohao
    Dong, Xinzhong
    SEMINARS IN IMMUNOPATHOLOGY, 2016, 38 (03) : 293 - 307
  • [36] TRP channels: An overview
    Pedersen, SF
    Owsianik, G
    Nilius, B
    CELL CALCIUM, 2005, 38 (3-4) : 233 - 252
  • [37] TRP Channels in Excitotoxicity
    Zong, Pengyu
    Legere, Nicholas
    Feng, Jianlin
    Yue, Lixia
    NEUROSCIENTIST, 2025, 31 (01): : 80 - 97
  • [38] TRP channels in the skin
    Toth, Balazs I.
    Olah, Attila
    Szoellosi, Attila Gabor
    Biro, Tamas
    BRITISH JOURNAL OF PHARMACOLOGY, 2014, 171 (10) : 2568 - 2581
  • [39] TRP channels in itch and pain
    Tominaga, Makoto
    ACTA DERMATO-VENEREOLOGICA, 2007, 87 (05) : 466 - 466
  • [40] TRP Channels in Brain Tumors
    Chinigo, Giorgia
    Castel, Helene
    Chever, Oana
    Gkika, Dimitra
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 9
12345