Omalizumab and allergen immunotherapy for respiratory allergies: A mini-review from the Allergen-Immunotherapy Committee of the Italian Society of Pediatric Allergy and Immunology (SIAIP)

被引：7
|
作者：
De Filippo, Maria [1 ,2 ]
Votto, Martina [1 ,2 ]
Caminiti, Lucia [3 ]
Carella, Francesco [4 ]
De Castro, Giovanna [5 ]
Landi, Massimo [6 ,7 ,8 ]
Olcese, Roberta [9 ]
Panasiti, Ilenia [3 ]
Vernich, Mario [10 ]
Barberi, Salvatore [10 ]
Ciprandi, Giorgio [11 ]
Marseglia, Gian Luigi [1 ,2 ]
机构：
[1] Univ Pavia, Dept Clin Surg Diagnost & Pediat Sci, Pavia, Italy
[2] Fdn IRCCS Policlin San Matteo, Pediat Clin, Pavia, Italy
[3] Univ Messina, Allergy Unit, Dept Pediat, Messina, Italy
[4] Azienza Osped Univ Policlin Giovanni XXIII, Pediatr Unit, Bari, Italy
[5] Sapienza Univ Rome, Dept Pediat, Rome, Italy
[6] Pediat Natl Hlthcare Syst, Turin, Italy
[7] Italian Natl Res Council, Ist Biomed Immunol Mol, Palermo, Italy
[8] CNR, Inst Biomed Res & Innovat, Dept Biomed, Palermo, Italy
[9] Ist Giannina Gaslini, Allergy Ctr, Dept Pediat, Genoa, Italy
[10] ASST Rhodense, Pediat Unit, Milan, Italy
[11] Casa Cura Villa Montallegro, Allergy Clin, Genoa, Italy
来源：
ALLERGOLOGIA ET IMMUNOPATHOLOGIA | 2022年 / 50卷 / 06期
关键词：
Allergen Immunotherapy; Omalizumab; IgE; Tolerance; Allergic Rhinitis; Asthma; SUBCUTANEOUS IMMUNOTHERAPY; BIOLOGICAL THERAPIES; CHILDREN; PRETREATMENT; COMBINATION; SAFETY; ADOLESCENTS; EFFICACY; UPDATE; ASTHMA;
D O I：
10.15586/aei.v50i6.495
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Although currently approved to treat severe asthma and chronic spontaneous urticaria, omalizumab has also been an effective and safe add-on treatment for other allergic diseases. Namely, omalizumab has been proposed to be used as add-on therapy in patients with allergic rhinitis and asthma and undergoing specific allergen immunotherapy (AIT). AIT is the only treatment that modifies the natural history of IgE-mediated diseases. This brief review summarizes the available evidence and controversies on the efficacy and safety of omalizumab combined with specific AIT. (c) 2022 Codon Publications. Published by Codon Publications.
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收藏
页码：47 / 52
页数：6
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