Enantioselective direct-addition of terminal alkynes to imines catalyzed by copper(I)pybox complex in water and in toluene

被引：493
|
作者：
Wei, CM [1 ]
Li, CJ [1 ]
机构：
[1] Tulane Univ, Dept Chem, New Orleans, LA 70118 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2002年 / 124卷 / 20期
关键词：
D O I：
10.1021/ja026007t
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Highly enantioselective direct alkyne-imine additions catalyzed by Cu(I)OTf and Evan's pybox ligands were developed in water and in toluene. The process is simple and provides a diverse range of propargylic amine in high ee and good yield. Copyright © 2002 American Chemical Society.
引用
收藏
页码：5638 / 5639
页数：2
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