Physical activity and cardiovascular disease risk in middle-aged and older women

被引:0
|
作者
Sesso, HD
Paffenbarger, RS
Ha, T
Lee, IM
机构
[1] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02115 USA
[3] Harvard Univ, Sch Med, Boston, MA 02115 USA
[4] Stanford Univ, Sch Med, Div Epidemiol, Stanford, CA 94305 USA
关键词
cardiovascular diseases; exercise; physical fitness; prospective studies; risk factors; women;
D O I
暂无
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The authors investigated the relation between physical activity and cardiovascular disease (CVD) in women by following 1,564 University of Pennsylvania alumnae (mean age, 45.5 years), initially free of CVD, from 1962 until 1993. Energy expenditure was estimated from the daily number of flights of stairs climbed and blocks walked as well as the sports played and was categorized into approximate thirds (<500, 500-999, greater than or equal to 1,000 kcal/week). During 35,021 person-years, 181 CVD cases were identified. After adjustment for coronary risk factors, the relative risks of CVD were 0.99 (95% confidence interval (CI): 0.69, 1.41) and 0.88 (95% CI: 0.62, 1.25) for women who expended 500-999 and greater than or equal to 1,000, respectively, compared with <500 kcal/week (p for trend = 0.45). Only walking was found to be inversely related to CVD risk (p for trend = 0.054). Compared with women who walked <4 blocks/day, the relative risks of CVD were 0.84 (95% CI: 0.59, 1.19) and 0.67 (95% CI: 0.45, 1.01) for women who walked 4-9 and greater than or equal to 10 blocks/day, respectively. Finally, an interaction (p = 0.023) between body mass index and physical activity on CVD risk was observed, with an inverse association only for leaner (<23 kg/m(2)) women. These data showed no overall association of physical activity with CVD risk in women. However, walking greater than or equal to 10 blocks/day (approximately 6 miles (9.7 km)/week) was associated with a 33% decreased risk. One explanation for this finding may be that walking was reported more precisely than other kinds of activities.
引用
收藏
页码:408 / 416
页数:9
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