GENETIC VARIABILITY OF BOLA-DRB3.2 GENE IN KENKATHA BREED OF CATTLE ASSESSED BY PCR-SSCP

被引：0
|
作者：
Ranjan, Rakesh [1 ]
Bhong, C. D. [1 ]
Chavan, K. N. [1 ]
Parmar, S. N. S. [1 ]
Joshi, C. G. [1 ]
机构：
[1] MPPCVV, Anim Biotechnol Ctr, Jabalpur 482004, India
来源：
INDIAN JOURNAL OF ANIMAL RESEARCH | 2013年 / 47卷 / 02期
关键词：
BoLA; Kenkatha; PCR; -SSCP; MHC;
D O I：
暂无
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
Present study was conducted to investigate BOLA (Bovine leucocyte antigen) gene polymorphism in indigenous draft Kenkatha (n=52) breed of cattle at DRB3.2 loci by PCR-SSCP (Single strand conformational polymorphism). This BoLA region encodes cell surface glycoprotein, which binds to foreign antigens of T lymphocytes that play central role in the induction and regulation of adaptive immunity. A PCR-SSCP of 284bp amplicon of BoLA-DRB3.2 gene revealed 13 SSCP patterns. This suggests that exon 2 region of BoLA-DRB3 is highly polymorphic in nature. This may be due to natural selection on a BoLA allele pool, leading to the development of resistance to local infectious diseases.
引用
收藏
页码：164 / 167
页数：4
相关论文
共 45 条
  • [1] Genetic Polymorphism of BoLA-DRB3.2 Locus in Ukrainian Cattle Breeds
    T. M. Suprovych
    Yu. T. Salyha
    M. P. Suprovych
    E. I. Fedorovych
    V. V. Fedorovych
    I. O. Chornyj
    Cytology and Genetics, 2022, 56 : 319 - 330
  • [2] Genetic Polymorphism of BoLA-DRB3.2 Locus in Ukrainian Cattle Breeds
    Suprovych, T. M.
    Salyha, Yu T.
    Suprovych, M. P.
    Fedorovych, E., I
    Fedorovych, V. V.
    Chornyj, I. O.
    CYTOLOGY AND GENETICS, 2022, 56 (04) : 319 - 330
  • [3] Genetic polymorphism of BoLA-DRB3.2 locus in crossbred cattle as revealed by PCR-RFLP analysis
    Ganguly, I
    Sarma, A
    De, S
    Mitra, A
    INDIAN JOURNAL OF ANIMAL SCIENCES, 2004, 74 (02): : 195 - 199
  • [4] DNA polymorphism of BoLA-DRB3.2 gene in Tharparkar cattle (Bos indicus) by PCR-RFLP
    Bhushan, Bharat
    Patra, B. N.
    Paswan, Chandan
    Umang
    Kumar, Pushpendra
    Dutt, Triveni
    Das, P. J.
    Sharma, Arjava
    Ahlawat, S. P. S.
    JOURNAL OF APPLIED ANIMAL RESEARCH, 2007, 32 (02) : 187 - 190
  • [5] BoLA-DRB3.2 Gene Polymorphism in Cattle Naturally Infected with Bovine Leukemia Virus
    Avci, Oguzhan
    Bulut, Oya
    Dik, Irmak
    Bulut, Zafer
    Dogan, Muge
    Kale, Mehmet
    Hasircioglu, Sibel
    Yapici, Orhan
    Simsek, Atilla
    Yavru, Sibel
    Orta, Yakup Sinan
    PAKISTAN VETERINARY JOURNAL, 2023, 43 (01) : 174 - 178
  • [6] Association of BoLA-DRB3.2 locus with bovine milk production in Gir breed
    Machado, MA
    Nascimento, CS
    Martinez, ML
    Silva, MVGB
    Campos, AL
    Teodoro, RL
    Verneque, RS
    Guimarnes, SEF
    ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA, 2005, 57 (03) : 380 - 389
  • [7] The association of BoLA-DRB3.2 alleles to clinical mastitis in Iranian Holstein and Sarabi (Iranian native) breed cattle
    Firouzamandi, Masomeh
    Bonyadi, Morteza
    Shoja, Jalil
    Gorbai, Aboulfazl
    Barzgar, Aboulfazl
    Roshani, Esmaeil
    TISSUE ANTIGENS, 2009, 73 (05): : 523 - 523
  • [8] Association of BLV infection profiles with alleles of the BoLA-DRB3.2 gene
    Juliarena, M. A.
    Poli, M.
    Sala, L.
    Ceriani, C.
    Gutierrez, S.
    Dolcini, G.
    Rodriguez, E. M.
    Marino, B.
    Rodriguez-Dubra, C.
    Esteban, E. N.
    ANIMAL GENETICS, 2008, 39 (04) : 432 - 438
  • [9] Association of BoLA-DRB3.2 alleles with tick (Boophilus microplus) resistance in cattle
    Martinez, M. L.
    Machado, M. A.
    Nascimento, C. S.
    Silva, M. V. G. B.
    Teodoro, R. L.
    Furlong, J.
    Prata, C. A.
    Campos, A. L.
    Guimaraes, M. F. M.
    Azevedo, A. L. S.
    Pires, M. F. A.
    Verneque, R. S.
    GENETICS AND MOLECULAR RESEARCH, 2006, 5 (03): : 513 - 524
  • [10] Intrabreed and interbreed variation of the BOLA-DRB3.2 gene in the Kostroma and Yaroslavl indigenous Russian cattle breeds
    Irina V. Lazebnaya
    Aleksey V. Perchun
    Oleg E. Lazebny
    Immunogenetics, 2020, 72 : 355 - 366
12345