Allosteric Modulators of Metabotropic Glutamate Receptors as Promising Therapeutic Strategies for Alzheimer's Disease

被引：0
|
作者：
Rook, Jerri M. [1 ,2 ]
Dickerson, Jonathan W. [1 ,2 ]
Ghoshal, Ayan [1 ,2 ]
Walker, Adam G. [1 ,2 ]
Roop, Gregory N. [1 ,2 ]
Huan, Qiuwei [1 ,2 ]
Stauffer, Shaun R. [1 ,2 ,3 ]
Niswender, Colleen M. [1 ,2 ]
Daniels, J. Scott [1 ,2 ]
Jones, Carrie K. [1 ,2 ]
Lindsley, Craig W. [1 ,2 ,3 ]
Conn, P. Jeffrey [1 ,2 ]
机构：
[1] Vanderbilt Univ, Med Ctr, Dept Pharmacol, Nashville, TN 37232 USA
[2] Vanderbilt Univ, Med Ctr, Vanderbilt Ctr Neurosci Drug Discovery, Nashville, TN 37232 USA
[3] Vanderbilt Univ, Med Ctr, Dept Chem, Nashville, TN 37232 USA
来源：
CURRENT NEUROPHARMACOLOGY | 2014年 / 12卷
关键词：
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
138
引用
收藏
页码：53 / 53
页数：1
相关论文
共 50 条
  • [21] Allosteric modulators of group I metabotropic glutamate receptors: novel subtype-selective ligands and therapeutic perspectives
    Gasparini, F
    Kuhn, R
    Pin, JP
    CURRENT OPINION IN PHARMACOLOGY, 2002, 2 (01) : 43 - 49
  • [22] Positive Allosteric Modulators of Trk Receptors for the Treatment of Alzheimer's Disease
    Forsell, Pontus
    Fernandez, Cristina Parrado
    Nilsson, Boel
    Sandin, Johan
    Nordvall, Gunnar
    Segerdahl, Maerta
    PHARMACEUTICALS, 2024, 17 (08)
  • [23] Pharmacological properties and therapeutic potential of allosteric potentiators of metabotropic glutamate receptors
    Conn, PJ
    Hemstapat, A
    Rodriguez, AL
    Chen, Y
    Nong, Y
    Jones, C
    DePaulis, T
    Zhang, Y
    Tamagnan, G
    NEUROPHARMACOLOGY, 2005, 49 : 240 - 240
  • [24] Allosteric modulation of metabotropic glutamate receptors: Structural insights and therapeutic potential
    Gregory, Karen J.
    Dong, Elizabeth N.
    Meiler, Jens
    Conn, P. Jeffrey
    NEUROPHARMACOLOGY, 2011, 60 (01) : 66 - 81
  • [25] Therapeutic potential of targeting metabotropic glutamate receptors for Parkinson's disease
    Dickerson, Jonathan W.
    Conn, P. Jeffrey
    NEURODEGENERATIVE DISEASE MANAGEMENT, 2012, 2 (02) : 221 - 232
  • [26] A novel family of potent negative allosteric modulators of group II metabotropic glutamate receptors
    Hemstapat, Kamondanai
    Da Costa, Herve
    Nong, Yi
    Brady, Ashley E.
    Luo, Qingwei
    Niswender, Colleen M.
    Tamagnan, Gilles D.
    Conn, P. Jeffrey
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2007, 322 (01): : 254 - 264
  • [27] Preferential binding of allosteric modulators to active and inactive conformational states of metabotropic glutamate receptors
    Yanamala, Naveena
    Tirupula, Kalyan C.
    Klein-Seetharaman, Judith
    BMC BIOINFORMATICS, 2008, 9 (Suppl 1)
  • [28] Novel allosteric modulators of metabotropic glutamate receptors subtypes 2 and 5 for the treatment of schizophrenia
    Jones, C. K.
    Xiang, Z.
    Jones, P. J.
    Byun, N. E.
    Hackler, E. A.
    Rodriguez, A. L.
    Ayala, J. E.
    Niswender, C. M.
    Jadhav, S.
    Sheffler, D. J.
    Hammond, A. S.
    Barret, R.
    Thompson, A. D.
    Williams, R.
    Gore, J. C.
    Weaver, C. D.
    Lindsley, C. W.
    Conn, P. J.
    NEUROPHARMACOLOGY, 2008, 55 (04) : 603 - 603
  • [29] Special Issue on the Pharmacology and Medicinal Chemistry of Allosteric Modulators of Metabotropic Glutamate Receptors (mGluRs)
    Lindsley, Craig W.
    ACS CHEMICAL NEUROSCIENCE, 2011, 2 (08): : 379 - 379
  • [30] Preferential binding of allosteric modulators to active and inactive conformational states of metabotropic glutamate receptors
    Naveena Yanamala
    Kalyan C Tirupula
    Judith Klein-Seetharaman
    BMC Bioinformatics, 9
12345