Polypeptide deformylase inhibitors: Design, synthesis and evaluation of a novel benzamide scaffold.

被引：0

作者：

Karpinski, JM

Christensen, SB

Aubart, KM

Van Aller, GS

DeMarsh, PL

Lewandowski, TF

Rittenhouse, S

Kulkarni, SG

McIntyre, TA

Woods, LC

Lonetto, MA

Pearson, SC

Smith, KJ

Bhat, A

Cummings, M

Saylers, K

机构：

[1] GlaxoSmithKline Inc, Dept Med Chem, Collegeville, PA 19426 USA

[2] GlaxoSmithKline Inc, Dept Enzymol, Collegeville, PA USA

[3] GlaxoSmithKline Inc, Dept Microbiol, Collegeville, PA USA

[4] GlaxoSmithKline Inc, Dept Drug Metab & Pharmacokinet, Collegeville, PA USA

[5] GlaxoSmithKline Inc, Dept Genet Res, Collegeville, PA USA

[6] GlaxoSmithKline Inc, Dept Computat & Struct Sci, Collegeville, PA USA

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 229卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

360-MEDI

引用

页码：U173 / U173

页数：1

共 50 条

[41] Design, Synthesis, and Evaluation of PD-1/PD-L1 Antagonists Bearing a Benzamide Scaffold
Lu, Lu
Qi, Zhihao
Wang, Tianyu
Zhang, Xiangyu
Zhang, Kuojun
Wang, Kaizhen
Cheng, Yao
Xiao, Yibei
Li, Zheng
Jiang, Sheng
ACS MEDICINAL CHEMISTRY LETTERS, 2022, 13 (04): : 586 - 592
[42] Design and synthesis of inhibitors of noroviruses by scaffold hopping
Dou, Dengfeng
Mandadapu, Sivakoteswara Rao
Alliston, Kevin R.
Kim, Yunjeong
Chang, Kyeong-Ok
Groutas, William C.
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 19 (19) : 5749 - 5755
[43] Design, synthesis and initial biological evaluation of a novel pladienolide analog scaffold
Gundluru, Mahesh Kumar
Pourpak, Alan
Cui, Xiaoli
Morris, Stephan W.
Webb, Thomas R.
MEDCHEMCOMM, 2011, 2 (09) : 904 - 908
[44] Development of 9H-purine scaffold as novel CDK2 inhibitors: Design, synthesis, and biological evaluation
Zhang, Yan
Liu, Xiya
Li, Ziming
Wang, Xia
Tang, Chunlei
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 122
[45] Design, synthesis and biological evaluation of novel xanthine oxidase inhibitors bearing a 2-arylbenzo[b]furan scaffold
Tang, Hong-Jin
Li, Wei
Zhou, Mei
Peng, Li-Ying
Wang, Jin-Xin
Li, Jia-Huang
Chen, Jun
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 151 : 849 - 860
[46] Total synthesis of ( plus /-)-fumimycin and analogues for biological evaluation as peptide deformylase inhibitors
Zaghouani, Mehdi
Boegeholz, Lena A. K.
Mercier, Evan
Wintermeyer, Wolfgang
Roche, Stephane P.
TETRAHEDRON, 2019, 75 (24) : 3216 - 3230
[47] In silico, synthesis and anticancer evaluation of benzamide tryptamine derivatives as novel eEF2K inhibitors
Liu, Zedong
Jiang, Aili
Wang, Yaqi
Xu, Pei
Zhang, Qiting
Wang, Yinda
He, Shan
Wang, Ning
Jin, Haixiao
Zhang, Bin
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 67
[48] Design, synthesis, and biological evaluation of the combinatorial library with a new spirodiketopiperazine scaffold. Discovery of novel potent and selective low-molecular-weight CCR5 antagonists
Habashita, Hiromu
Kokubo, Masaya
Hamano, Shin-ichi
Hamanaka, Nobuyuki
Toda, Masaaki
Shibayama, Shiro
Tada, Hideaki
Sagawa, Kenji
Fukushima, Daikichi
Maeda, Kenji
Mitsuya, Hiroaki
JOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (14) : 4140 - 4152
[49] Design, synthesis, and antitumor evaluation of histone deacetylase inhibitors with L-phenylglycine scaffold
Zhang, Yingjie
Li, Xiaoguang
Hou, Jinning
Huang, Yongxue
Xu, Wenfang
DRUG DESIGN DEVELOPMENT AND THERAPY, 2015, 9 : 5553 - 5567
[50] Design, synthesis and docking studies on benzamide derivatives as histone deacetylase inhibitors
Lu, Aijun
Luo, Hongpeng
Shi, Minfeng
Wu, Gang
Yuan, Yunxia
Liu, Jian
Tang, Feng
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21 (16) : 4924 - 4927

← 1 2 3 4 5 →