Bone Marrow MMP-9 Expression Mediates Therapeutic Effect of Selective CXCR4 Antagonist AMD3100 on Myocardial Infarction

被引:0
|
作者
Jujo, Kentaro [1 ]
Ii, Masaaki [2 ]
Sekiguchi, Haruki [1 ]
Hamada, Hiromichi [1 ]
Thorne, Tina [1 ]
Klyachko, Ekaterina [1 ]
Clarke, Trevor [1 ]
Ito, Aiko [1 ]
Misener, Sol [1 ]
Renault, Marie-Ange [1 ]
Losordo, Douglas W. [1 ]
机构
[1] Northwestern Univ, Feinberg Sch, Chicago, IL 60611 USA
[2] Inst BioMed Rsch & Innovat, Kobe, Hyogo, Japan
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:S536 / S537
页数:2
相关论文
共 50 条
  • [41] Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist
    Broxmeyer, HE
    Orschell, CM
    Clapp, DW
    Hangoc, G
    Cooper, S
    Plett, PA
    Liles, WC
    Li, XX
    Graham-Evans, B
    Campbell, TB
    Calandra, G
    Bridger, G
    Dale, DC
    Srour, EF
    JOURNAL OF EXPERIMENTAL MEDICINE, 2005, 201 (08): : 1307 - 1318
  • [42] Recent advances on the use of the CXCR4 antagonist plerixafor (AMD3100, Mozobil™) and potential of other CXCR4 antagonists as stem cell mobilizers
    De Clercq, Erik
    PHARMACOLOGY & THERAPEUTICS, 2010, 128 (03) : 509 - 518
  • [43] Chronic AMD3100 antagonism of SDF-1α-CXCR4 exacerbates cardiac dysfunction and remodeling after myocardial infarction
    Dai, Shujing
    Yuan, Fangping
    Mu, Jingyao
    Li, Chengxin
    Chen, Ning
    Guo, Shangzhi
    Kingery, Justin
    Prabhu, Sumanth D.
    Bolli, Roberto
    Rokosh, Gregg
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2010, 49 (04) : 587 - 597
  • [44] CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy
    Azab, Abdel Kareem
    Runnels, Judith M.
    Pitsillides, Costas
    Moreau, Anne-Sophie
    Azab, Feda
    Leleu, Xavier
    Jia, Xiaoying
    Wright, Renee
    Ospina, Beatriz
    Carlson, Alicia L.
    Alt, Clemens
    Burwick, Nicholas
    Roccaro, Aldo M.
    Ngo, Hai T.
    Farag, Mena
    Melhem, Molly R.
    Sacco, Antonio
    Munshi, Nikhil C.
    Hideshima, Teru
    Rollins, Barrett J.
    Anderson, Kenneth C.
    Kung, Andrew L.
    Lin, Charles P.
    Ghobrial, Irene M.
    BLOOD, 2009, 113 (18) : 4341 - 4351
  • [45] CXCR4-selective antagonist AMD3100 accelerates impaired wound healing in diabetic mice
    Nishimura, Y.
    Ii, M.
    Asai, J.
    Takenaka, H.
    Katoh, N.
    Hamada, H.
    Qin, G.
    Losordo, D. W.
    Kishimoto, S.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2009, 129 : S4 - S4
  • [46] CXCR4 and MMP-9 in prostate cancer bone metastasis
    Chinni, SR
    Dong, Z
    Sivalogan, S
    Trindade, JC
    Bhagat, S
    Bonfil, R
    Cher, ML
    JOURNAL OF BONE AND MINERAL RESEARCH, 2004, 19 (09) : 1577 - 1578
  • [47] CXCR4 Antagonist AMD3100 Reverses the Resistance to Tamoxifen in Breast Cancer via Inhibiting AKT Phosphorylation
    Zhou, Jun
    Le, Kehao
    Xu, Ming
    Ming, Jie
    Yang, Wen
    Zhang, Qiulei
    Lu, Linlin
    Xi, Zihan
    Ruan, Shengnan
    Huang, Tao
    MOLECULAR THERAPY ONCOLYTICS, 2020, 18 : 161 - 170
  • [48] The SDF-1/CXCR4 pathway is involved in the homing of chronic lymphocytic leukemia B cells and in their survival after migration into bone marrow stromal layers: inhibition by the CXCR4 antagonist (AMD3100)
    Lagneaux, L
    Delforge, A
    Dejeneffe, M
    Schols, D
    Bron, D
    EXPERIMENTAL HEMATOLOGY, 2002, 30 (06) : 54 - 54
  • [49] Evaluation of CXCR4 expression in experimental brain tumor xenografts with [64Cu]AMD3100
    Nimmagadda, Sridhar
    Pullambhatla, Mrudula
    Green, Gilbert
    Bhujwalla, Zaver
    Pomper, Martin
    JOURNAL OF NUCLEAR MEDICINE, 2010, 51
  • [50] Suppression of dualtropic human immunodeficiency virus type 1 by the CXCR4 antagonist AMD3100 is associated with efficiency of CXCR4 use and baseline virus composition
    Fransen, Signe
    Bridger, Gary
    Whitcomb, Jeannette M.
    Toma, Jonathan
    Stawiski, Eric
    Parkin, Neil
    Petropoulos, Christos J.
    Huang, Wei
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (07) : 2608 - 2615