Type 2 Biomarkers and Eosinophil Activation in Severe Asthma and the Impact of Mepolizumab

被引:0
|
作者
Howarth, P. [1 ]
Quirce, S. [2 ,3 ]
Papi, A. [4 ,5 ]
Israel, E. [6 ,7 ]
Mallett, S. [8 ]
Bates, S. [9 ]
Albers, F. C. [10 ]
Kwon, N. [11 ]
机构
[1] GSK House, Global Med Franchise, Brentford, England
[2] Hosp La Paz Inst Hlth Res IdiPAZ, Dept Allergy, Madrid, Spain
[3] Inst Carlos III, CIBERES, Madrid, Spain
[4] Univ Ferrara, Dept Med Sci, Ferrara, Italy
[5] S Anna Univ Hosp, Ferrara, Italy
[6] Harvard Med Sch, Boston, MA 02115 USA
[7] Brigham & Womens Hosp, Asthma Res Ctr, 75 Francis St, Boston, MA 02115 USA
[8] GSK, Biostat, Stockley Pk, Uxbridge, Middx, England
[9] GSK, Resp Discovery Med, Stevenage, Herts, England
[10] GSK, Resp Med Franchise, Res Triangle Pk, NC USA
[11] GSK, Resp Med Franchise, London, England
关键词
D O I
暂无
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A1275
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Mepolizumab Attenuates Airway Eosinophil Numbers, but Not Their Functional Phenotype, in Asthma
    Kelly, Elizabeth A.
    Esnault, Stephane
    Liu, Lin Ying
    Evans, Michael D.
    Johansson, Mats W.
    Mathur, Sameer
    Mosher, Deane F.
    Denlinger, Loren C.
    Jarjour, Nizar N.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 196 (11) : 1385 - 1395
  • [32] Blood Eosinophil Depletion with Mepolizumab, Benralizumab, and Prednisolone in Eosinophilic Asthma
    Moran, Angela M.
    Ramakrishnan, Sanjay
    Borg, Catherine A.
    Connolly, Clare M.
    Couillard, Simon
    Mwasuku, Christine M.
    Pavord, Ian D.
    Hinks, Timothy S. C.
    Lehtimaki, Lauri
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2020, 202 (09) : 1314 - 1316
  • [33] Eosinophil activation with autophagy and extracellular DNA traps is involved in severe asthma
    Pham, D. L.
    Ban, G.
    Kim, S.
    Park, H.
    ALLERGY, 2017, 72 : 182 - 182
  • [34] IMPACT OF WEIGHT ON STEROID REDUCTION IN PATIENTS WITH SEVERE EOSINOPHILIC ASTHMA TREATED WITH MEPOLIZUMAB
    Katial, R.
    Albers, F.
    Prazma, C.
    Bradford, E.
    Ortega, H.
    Price, R.
    Pouliquen, I.
    Castro, M.
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2017, 119 (05) : E3 - E3
  • [35] The impact of treatment with omalizumab, mepolizumab, benralizumab, dupilumab and tezepelumab in patients with severe asthma
    Mochizuki, Taichi
    Inoue, Yasushi
    Ueda, Ryuta
    Nagase, Seisuke
    Kuwano, Kazuyoshi
    Umeda, Akira
    To, Yasuo
    RESPIROLOGY, 2023, 28 : 339 - 340
  • [36] Severe eosinophilic asthma treated with mepolizumab stratified by baseline eosinophil thresholds: a secondary analysis of the DREAM and MENSA studies
    Ortega, Hector G.
    Yancey, Steven W.
    Mayer, Bhabita
    Gunsoy, Necdet B.
    Keene, Oliver N.
    Bleecker, Eugene R.
    Brightling, Christopher E.
    Pavord, Ian D.
    LANCET RESPIRATORY MEDICINE, 2016, 4 (07): : 549 - 556
  • [37] International Differences in the Use of Mepolizumab to Treat Severe Asthma Impact of Reimbursement Policies
    Chaudhuri, R.
    Caruso, C.
    Chupp, G.
    Fera, T.
    Koehler, T.
    Schleich, F.
    Valero, A.
    Yang, S.
    Howarth, P.
    Jakes, R. W.
    Maxwell, A. C.
    Price, R. G.
    Cristancho, R. Alfonso
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2021, 203 (09)
  • [38] The impact of treatment with omalizumab, mepolizumab, benralizumab, dupilumab and tezepelumab in patients with severe asthma
    Mochizuki, Taichi
    Inoue, Yasushi
    Ueda, Ryuta
    Nagase, Seisuke
    Kuwano, Kazuyoshi
    Umeda, Akira
    To, Yasuo
    Sakao, Seiichiro
    RESPIROLOGY, 2024, 29 : 97 - 98
  • [39] Effect Of Mepolizumab On Health Status, Lung Function And Asthma Control According To Baseline Blood Eosinophil Count In Patients With Severe Eosinophilic Asthma
    Trevor, J. L.
    Albers, F. C.
    Nelsen, L. M.
    Bratton, D. J.
    Wang-Jairaj, J.
    Bradford, E.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 195
  • [40] Clinical usefulness of mepolizumab in severe eosinophilic asthma
    Menzella, Francesco
    Lusuardi, Mirco
    Montanari, Gloria
    Galeone, Carla
    Facciolongo, Nicola
    Zucchi, Luigi
    THERAPEUTICS AND CLINICAL RISK MANAGEMENT, 2016, 12 : 907 - 916