Antifungal activity and some novel organo-phosphorus compounds: Preparation and spectral characterization

The inhibitory effects of a recently introduced series of N-phosphorylated/thiophosphorylated compounds on Aspergillus niger and Fusarium oxysporium were examined. The derivatives were obtained in good yield by reacting 2-(2'-aminophenyl)benzoxazole with phosphorous oxychloride and thiophosphoryl chloride in different molar ratios (1:1, 2:1, and 3:1). Structure elucidation of all synthesized compounds was based on the data of elemental analysis, IR, H-1 NMR, and P-31 NMR spectra.