The cAMP responsive Rap1 guanine nucleotide exchange factor, Epac, induces smooth muscle relaxation by down regulation of RhoA activity

被引：0

作者：

Zieba, Bartosz Jakub ^{[1
,2
]}

Artamonov, Mykhaylo V. ^{[2
]}

Jin, Li ^{[2
]}

Momotani, Ko ^{[2
]}

Ho, Ruoya ^{[2
]}

Franke, Aaron S. ^{[2
]}

Neppl, Ronald L. ^{[2
]}

Stevenson, Andra S. ^{[2
]}

Khromov, Alexander S. ^{[2
]}

Chrzanowska-Wodnicka, Magdalena ^{[3
]}

Somlyo, Avril V. ^{[2
]}

机构：

[1] Jagiellonian Univ, Dept Cell Biochem, Krakow, Poland

[2] Univ Virginia, Dept Mol Physiol & Biol Phys, Charlottesville, VA USA

[3] Blood Ctr SE Wisconsin Inc, Blood Res Inst, Milwaukee, WI 53233 USA

来源：

FASEB JOURNAL | 2011年 / 25卷

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页数：1

共 45 条

[11] cAMP-mediated relaxation of vascular smooth muscle through an Epac-Rap1 GTPase pathway
Stevenson, A. S.
Khromov, A. S.
Neppl, R. L.
Momotani, K.
Jin, L.
Somlyo, A. V.
BIOPHYSICAL JOURNAL, 2007, : 39A - 40A
[12] The Rap1 Guanine Nucleotide Exchange Factor C3G Is Required for Preservation of Larval Muscle Integrity in Drosophila melanogaster
Shirinian, Margret
Grabbe, Caroline
Popovic, Milica
Varshney, Gaurav
Hugosson, Fredrik
Bos, Hans
Rehmann, Holger
Palmer, Ruth H.
PLOS ONE, 2010, 5 (03):
[13] Expression of the Rap1 Guanine Nucleotide Exchange Factor, MR-GEF, Is Altered in Individuals with Bipolar Disorder
Bithell, Angela
Hsu, Tony
Kandanearatchi, Apsara
Landau, Sabine
Everall, Ian P.
Tsuang, Ming T.
Chana, Gursharan
Williams, Brenda P.
PLOS ONE, 2010, 5 (04):
[14] Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504
Ichiba, T
Hashimoto, Y
Nakaya, M
Kuraishi, Y
Tanaka, S
Kurata, T
Mochizuki, N
Matsuda, M
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (20) : 14376 - 14381
[15] Rap1 mutants with increased affinity for the guanine-nucleotide exchange factor C3G
Shi, SL
Noda, M
Kitayama, H
ONCOGENE, 2004, 23 (54) : 8711 - 8719
[16] Rap1 mutants with increased affinity for the guanine-nucleotide exchange factor C3G
Shuliang Shi
Makoto Noda
Hitoshi Kitayama
Oncogene, 2004, 23 : 8711 - 8719
[17] CAMP promotes migration of leukocytes toward stromal cell-derived factor-1 through activation of the Rap1 exchange factor Epac
不详
IMMUNOBIOLOGY, 2004, 209 (4-6) : 312 - 312
[18] cAMP activates RAP1 in differentiating mouse male germ cells: A new signaling pathway mediated by the cAMP-activated exchange factor Epac?
Berruti, G
CELLULAR AND MOLECULAR BIOLOGY, 2003, 49 (03) : 381 - 388
[19] The Rap1 guanine nucleotide exchange factor RA-GEF-1 is essential for the proper development of the mouse cerebral cortex
Bilasy, Shymaa E.
Satoh, Takaya
Terashima, Toshio
Kataoka, Tohru
NEUROSCIENCE RESEARCH, 2010, 68 : E432 - E432
[20] p130Cas regulates the activity of AND-34, a novel Ra1, Rap1, and R-Ras guanine nucleotide exchange factor
Gotoh, T
Cai, DP
Tian, XJ
Feig, LA
Lerner, A
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (39) : 30118 - 30123

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