Progress in the Development of Non-ATP-Competitive Protein Kinase Inhibitors for Oncology

被引:8
|
作者
McInnes, Campbell [1 ]
机构
[1] Univ S Carolina, S Carolina Coll Pharm, Columbia, SC 29208 USA
来源
ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 47 | 2012年 / 47卷
关键词
POLO-LIKE KINASE-1; BOX DOMAIN; DNA-DAMAGE; PEPTIDE INHIBITORS; RECRUITMENT-SITE; DESIGN; PHOSPHORYLATION; IDENTIFICATION; COMPLEX; POLO-LIKE-KINASE-1;
D O I
10.1016/B978-0-12-396492-2.00029-1
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页码:459 / 474
页数:16
相关论文
共 50 条
  • [41] GCN2 kinase activation by ATP-competitive kinase inhibitors
    Colin P. Tang
    Owen Clark
    John R. Ferrarone
    Carl Campos
    Alshad S. Lalani
    John D. Chodera
    Andrew M. Intlekofer
    Olivier Elemento
    Ingo K. Mellinghoff
    Nature Chemical Biology, 2022, 18 : 207 - 215
  • [42] GCN2 kinase activation by ATP-competitive kinase inhibitors
    Tang, Colin P.
    Clark, Owen
    Ferrarone, John R.
    Campos, Carl
    Lalani, Alshad S.
    Chodera, John D.
    Intlekofer, Andrew M.
    Elemento, Olivier
    Mellinghoff, Ingo K.
    NATURE CHEMICAL BIOLOGY, 2022, 18 (02) : 207 - +
  • [43] Allosteric and ATP-competitive kinase inhibitors of mTOR for cancer treatment
    Garcia-Echeverria, Carlos
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (15) : 4308 - 4312
  • [44] Crystal Structures of Anaplastic Lymphoma Kinase in Complex with ATP Competitive Inhibitors
    Bossi, Roberto T.
    Saccardo, M. Beatrice
    Ardini, Elena
    Menichincheri, Maria
    Rusconi, Luisa
    Magnaghi, Paola
    Orsini, Paolo
    Avanzi, Nilla
    Borgia, Andrea Lombardi
    Nesi, Marcella
    Bandiera, Tiziano
    Fogliatto, Gianpaolo
    Bertrand, Jay A.
    BIOCHEMISTRY, 2010, 49 (32) : 6813 - 6825
  • [45] Mitogen Activated Protein (MAP) Kinases: Development of ATP and Non-ATP Dependent Inhibitors
    Hancock, Chad N.
    Macias, Alba T.
    MacKerell, Alexander D., Jr.
    Shapiro, Paul
    MEDICINAL CHEMISTRY, 2006, 2 (02) : 213 - 222
  • [46] The therapeutic potential of a novel non-ATP-competitive fibroblast growth factor receptor 1 inhibitor on gastric cancer
    Xu, Chaochao
    Li, Wulan
    Qiu, Peihong
    Xia, Yiqun
    Du, Xiaojing
    Wang, Fen
    Shen, Lailai
    Chen, Qiuxiang
    Zhao, Yunjie
    Jin, Rong
    Wu, Jianzhang
    Liang, Guang
    Li, Xiaokun
    ANTI-CANCER DRUGS, 2015, 26 (04) : 379 - 387
  • [47] Detection of ATP competitive protein kinase inhibition by western blotting
    Wang, RX
    Thompson, JE
    ANALYTICAL BIOCHEMISTRY, 2001, 299 (01) : 110 - 112
  • [48] ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent
    Gumireddy, K
    Reddy, MVR
    Cosenza, SC
    Nathan, RB
    Baker, SJ
    Papathi, N
    Jiang, JD
    Holland, J
    Reddy, EP
    CANCER CELL, 2005, 7 (03) : 275 - 286
  • [49] Novel ATP-competitive kinesin spindle protein inhibitors
    Parrish, Cynthia A.
    Adams, Nicholas D.
    Auger, Kurt R.
    Burgess, Joelle L.
    Carson, Jeffrey D.
    Chaudhari, Amita M.
    Copeland, Robert A.
    Diamond, Melody A.
    Donatelli, Carla A.
    Duffy, Kevin J.
    Faucette, Leo F.
    Finer, Jeffrey T.
    Huffman, William F.
    Hugger, Erin D.
    Jackson, Jeffrey R.
    Knight, Steven D.
    Luo, Lusong
    Moore, Michael L.
    Newlander, Ken A.
    Ridgers, Lance H.
    Sakowicz, Roman
    Shaw, Antony N.
    Sung, Chiu-Mei M.
    Sutton, David
    Wood, Kenneth W.
    Zhang, Shu-Yun
    Zimmerman, Michael N.
    Dhanak, Dashyant
    JOURNAL OF MEDICINAL CHEMISTRY, 2007, 50 (20) : 4939 - 4952
  • [50] DIANILINOPHTHALIMIDES - POTENT AND SELECTIVE, ATP-COMPETITIVE INHIBITORS OF THE EGF-RECEPTOR PROTEIN-TYROSINE KINASE
    TRINKS, U
    BUCHDUNGER, E
    FURET, P
    KUMP, W
    METT, H
    MEYER, T
    MULLER, M
    REGENASS, U
    RIHS, G
    LYDON, N
    TRAXLER, P
    JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (07) : 1015 - 1027