Bacterial cell-to-cell communication: Sorry, can't talk now - gone to lunch!

被引：241
|
作者：
Winzer, K
Hardie, KR
Williams, P [1 ]
机构：
[1] Univ Nottingham, Queens Med Ctr, Inst Infect & Immun, Nottingham NG7 2UH, England
[2] Univ Nottingham, Sch Pharmaceut Sci, Nottingham NG7 2RD, England
来源：
CURRENT OPINION IN MICROBIOLOGY | 2002年 / 5卷 / 02期
关键词：
D O I：
10.1016/S1369-5274(02)00304-1
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The identification of novel bacterial cell-to-cell communication (quorum sensing) systems based on diffusible signal molecules, such as indole and the LuxS autoinducer-2, requires discrimination between true signalling molecules and metabolites present in culture supernatants. This depends on rigorous chemical characterisation and demonstration that the molecule controls cellular responses beyond those required to metabolise or detoxify the signal.
引用
收藏
页码：216 / 222
页数：7
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