Chiral induction controlled by aggregation of organometallics:: trifluoromethylated aminoalcohols for chiral ligands in Et2Zn alkylation of benzaldehyde

被引：25

作者：

Katagiri, T ^{[1
]}

Fujiwara, Y ^{[1
]}

Takahashi, S ^{[1
]}

Ozaki, N ^{[1
]}

Uneyama, K ^{[1
]}

机构：

[1] Okayama Univ, Dept Appl Chem, Okayama 7008530, Japan

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 09期

关键词：

D O I：

10.1039/b201238c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chiral induction in the reaction of Et2Zn with PhCHO by fluorinated chiral amino alcohols was correlated to the extent of aggregation of Et2Zn species, which was estimated by manometric study.

引用

页码：986 / 987

页数：2

共 8 条

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Mastranzo, Virginia M.
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TETRAHEDRON-ASYMMETRY, 2006, 17 (11) : 1663 - 1670
[2] Enantioselective addition of Et2Zn to aldehydes catalyzed by chiral aliphatic β-amino alcohols
Shen, ZX
Xu, XN
Liu, XF
Zhang, LF
Zhang, YW
CHINESE JOURNAL OF CHEMISTRY, 2000, 18 (04) : 582 - 584
[3] Asymmetric anionic polymerization of N-substituted maleimides with Et2Zn and chiral bisoxazolines
Onimura, K
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CHEMISTRY LETTERS, 1998, (08) : 791 - 792
[4] Modular amino alcohol ligands containing bulky alkyl groups as chiral controllers for Et2Zn addition to aldehydes:: Illustration of a design principle
Jimeno, C
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JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (08): : 3130 - 3138
[5] SYNTHESIS OF A NEW LINEAR CHIRAL POLYMER BASED ON POLYBINAPHTHOLS AND ITS APPLICATION IN ENANTIOSELECTIVE ADDITION OF Et2Zn TO ALDEHYDES
Wu, Ling-lin
Zheng, Li-fei
Huang, Xiao-bo
Cheng, Yi-xiang
ACTA POLYMERICA SINICA, 2013, (06) : 802 - 810
[6] Optimization of new chiral ligands for the copper-catalysed enantioselective conjugate addition of Et2Zn to nitroolefins by high-throughput screening of a parallel library
Ongeri, S
Piarulli, U
Jackson, RFW
Gennari, C
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2001, 2001 (04) : 803 - 807
[7] Highly Enantioselective Addition of Terminal Alkynes to Aldehydes Catalyzed by a New Chiral β-Sulfonamide Alcohol/Ti(OiPr)4/Et2Zn/R3N Catalyst System
Qiu, Li
Wang, Quan
Lin, Li
Liu, Xiaodong
Jiang, Xianxing
Zhao, Qingyang
Hu, Guowen
Wang, Rui
CHIRALITY, 2009, 21 (02) : 316 - 323
[8] Straightforward synthesis of [(2S,4R)-1-cyclohexyl-4-methylpiperidin-2-yl]methanol and [(2S,4R)-1-cyclohexyl-4-methylpiperidin-2-yl](diphenyl)methanol: novel chiral ligands for the catalytic addition of diethylzinc to benzaldehyde to give rise to an extensive turn in the sense of asymmetric induction
Alvarez-Ibarra, Carlos
Collados Lujan, Juan F.
Quiroga-Feijoo, Maria L.
TETRAHEDRON-ASYMMETRY, 2010, 21 (19) : 2334 - 2345

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