Hypothalamic-Amygdalar-Brainstem Volume Reduction in a Patient with Narcolepsy Secondary to Diffuse Axonal Injury

被引:16
|
作者
Yassin, Walid [1 ]
Sugihara, Genichi [1 ]
Oishi, Naoya [2 ]
Kubota, Manabu [1 ]
Ubukata, Shiho [1 ]
Murai, Toshiya [1 ]
Ueda, Keita [1 ]
机构
[1] Kyoto Univ, Grad Sch Med, Dept Psychiat, Kyoto, Japan
[2] Kyoto Univ, Grad Sch Med, Human Brain Res Ctr, Kyoto, Japan
来源
JOURNAL OF CLINICAL SLEEP MEDICINE | 2015年 / 11卷 / 05期
关键词
diffuse axonal injury; narcolepsy; hypothalamus; amygdala; MRI; LESIONS;
D O I
10.5664/jcsm.4710
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A 17-year-old male with diffuse axonal injury (DAI) was referred to our psychiatric clinic with a diagnosis of depression. However, further investigation indicated that he had narcolepsy without cataplexy secondary to DAI. We assessed regional volume alterations in the patient; MRI analysis showed a significant decrease in the volume of the hypothalamus, left amygdala, and brainstem. Our findings add to further understanding of the structural basis of secondary narcolepsy, and may provide basis for future neuroimaging studies on sleep disturbances in traumatic brain injury (TBI).
引用
收藏
页码:581 / 583
页数:3
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