Ln[N(SiMe3)2]3-catalyzed cycloaddition of terminal alkynes to azides leading to 1,5-disubstituted 1,2,3-triazoles: new mechanistic features

被引：105

作者：

Hong, Longcheng ^{[1
]}

Lin, Weijia ^{[1
]}

Zhang, Fangjun ^{[1
]}

Liu, Ruiting ^{[1
]}

Zhou, Xigeng ^{[1
,2
]}

机构：

[1] Fudan Univ, Shanghai Key Lab Mol Catalysis & Innovat Mat, Dept Chem, Shanghai 200433, Peoples R China

[2] State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 49期

基金：

中国国家自然科学基金;

关键词：

RUTHENIUM-CATALYZED CYCLOADDITION; 1,3-DIPOLAR CYCLOADDITIONS; CLICK-CHEMISTRY; TRIAZOLE; LIGATION; DIMERIZATION; SELECTIVITY; ACTIVATION; REACTIVITY; TETRAZOLES;

D O I：

10.1039/c3cc42534g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first example of rare earth metal-catalyzed cycloaddition of terminal alkynes to azides resulting in the formation of 1,5-disubstituted 1,2,3-triazoles is described. Preliminary studies revealed that the present cycloaddition shows unprecedented mechanistic features involving a tandem anionic cascade cyclization and anti-addition across the C C triple bond.

引用

页码：5589 / 5591

页数：3

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