Phage c31 Integrase Induces Chromosomal Aberrations in Primary Human Fibroblasts

被引:0
|
作者
Liu, Jian [1 ]
Jeppesen, Iben [1 ]
Nielsen, Kate [1 ]
Jensen, Thomas G. [1 ]
机构
[1] Natl Eye Clin, Kennedy Inst, Gene Therapy Lab, Glostrup, Denmark
关键词
D O I
10.1016/j.ymthe.2006.08.451
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
390
引用
收藏
页码:S149 / S149
页数:1
相关论文
共 50 条
  • [21] A novel nonviral approach to gene therapy for muscle disease mediated by phage φC31 integrase
    Wheeler, TM
    Jarrahian, S
    Bertoni, C
    Olivares, EC
    Contag, CH
    Calos, MP
    Rando, TA
    ANNALS OF NEUROLOGY, 2003, 54 : S43 - S43
  • [22] Phage C31 integrase mediated gene therapy in a mouse model of hereditary tyrosinemia type I
    Held, P
    Olivares, E
    Montini, E
    Finegold, M
    Calos, M
    Grompe, M
    AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 71 (04) : 584 - 584
  • [23] Sp100 interacts with phage (sic)C31 integrase to inhibit its recombination activity
    Lin, Yun
    Li, Zhi-hui
    Wang, Jing-Jing
    Xu, Gua-lan
    Shen, Qi
    Tian, Lin
    Xue, Jin-lun
    Chen, Jin-zhong
    ACTA BIOCHIMICA POLONICA, 2011, 58 (01) : 67 - 73
  • [24] A possible way that φC31 integrase regulates the recombination direction
    Liu, T. A.
    Fang, Y. X.
    Yin, H.
    Jing, Z. Z.
    GENETICS AND MOLECULAR RESEARCH, 2015, 14 (01) : 507 - 514
  • [25] Phage φC31 integrase-mediated genomic integration of the common cytokine receptor gamma chain in human T-cell lines
    Ishikawa, Yoshinori
    Tanaka, Nobuyuki
    Murakami, Kazuhiro
    Uchiyama, Toru
    Kumaki, Satoru
    Tsuchiya, Shigeru
    Kugoh, Hiroyuki
    Oshimura, Mitsuo
    Calos, Michele P.
    Sugamura, Kazuo
    JOURNAL OF GENE MEDICINE, 2006, 8 (05): : 646 - 653
  • [26] Cell type differences in activity of the Streptomyces bacteriophage φC31 integrase
    Maucksch, Christof
    Aneja, Manish Kumar
    Hennen, Elisabeth
    Bohla, Alexander
    Hoffmann, Florian
    Elfinger, Markus
    Rosenecker, Joseph
    Rudolph, Carsten
    NUCLEIC ACIDS RESEARCH, 2008, 36 (17) : 5462 - 5471
  • [27] ΦC31 Integrase Mediates Efficient Cassette Exchange in the Zebrafish Germline
    Hu, Gui
    Goll, Mary G.
    Fisher, Shannon
    DEVELOPMENTAL DYNAMICS, 2011, 240 (09) : 2101 - 2107
  • [28] Variable orthogonality of serine integrase interactions within the φC31 family
    MacDonald, Alasdair I.
    Baksh, Aron
    Holland, Alexandria
    Shin, Heewhan
    Rice, Phoebe A.
    Stark, W. Marshall
    Olorunniji, Femi J.
    SCIENTIFIC REPORTS, 2024, 14 (01):
  • [29] ΦC31 integrase interacts with TTRAP and inhibits NFκB activation
    Bing-yin Wang
    Guan-lan Xu
    Cai-hong Zhou
    Ling Tian
    Jing-lun Xue
    Jin-zhong Chen
    William Jia
    Molecular Biology Reports, 2010, 37 : 2809 - 2816
  • [30] The systemic effects of sclerostin overexpression using ΦC31 integrase in mice
    Zhang, Dongdong
    Park, Bo Mi
    Kang, Myengmo
    Nam, HeeJin
    Kim, Eun Jin
    Bae, ChuHyun
    Lim, Sung Kil
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 472 (03) : 471 - 476