Critical Role of TNF-α in the Expansion of Regulatory T Cells and Age Related Toxicity Following Immunotherapy

被引:0
|
作者
Alderson, Kory L. [1 ]
Bouchlaka, Myriam N. [1 ]
Wilkins, Danice E. [1 ]
Redelman, Doug [1 ]
Welniak, Lisbeth A. [1 ]
Murphy, William J. [1 ]
机构
[1] Univ Nevada, Dept Physiol, Reno, NV 89557 USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:957 / 957
页数:1
相关论文
共 50 条
  • [31] Treg cell: Critical role of regulatory T-cells in depression
    Gao, Xiao
    Tang, Yuru
    Kong, Lingli
    Fan, Yong
    Wang, Chunxia
    Wang, Rui
    PHARMACOLOGICAL RESEARCH, 2023, 195
  • [32] Bivalent structure of a TNFR2-selective and agonistic TNF-α mutein Fc-fusion protein enhances the expansion activity of regulatory T cells
    Masaki Inoue
    Yuta Tsuji
    Reira Ueno
    Daisuke Miyamoto
    Keisuke Tanaka
    Yuka Moriyasu
    Saya Shibata
    Mei Okuda
    Daisuke Ando
    Yasuhiro Abe
    Haruhiko Kamada
    Shin-ichi Tsunoda
    Scientific Reports, 13
  • [33] TNF-α inhibitors induce restoration of peripheral regulatory T cells and reduction of pro-inflammatory T cells in psoriatic skin lesions
    Jacobi, A.
    Carbone, T.
    Cavani, A.
    Greene, B. H.
    Moll, R.
    Hertl, M.
    Moebs, C.
    ZEITSCHRIFT FUR RHEUMATOLOGIE, 2014, 73 : 6 - 6
  • [34] A role for lymphatic endothelium in the sequestration of recirculating γδ T cells in TNF-α-stimulated lymph nodes
    Young, AJ
    Seabrook, TJ
    Marston, WL
    Dudler, L
    Hay, JB
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2000, 30 (01) : 327 - 334
  • [35] The effects and mechanisms of TNF-α/TNFR2 in regulatory T cells on microenvironment and progression in gastric cancer
    Qu, Yang
    Zhao, Gang
    Li, Hui
    CANCER RESEARCH, 2019, 79 (13)
  • [36] THE EFFECTS AND MECHANISMS OF TNF-α/TNFR2 IN REGULATORY T CELLS ON MICROENVIRONMENT AND PROGRESSION IN GASTRIC CANCER
    Qu, Y.
    Zhao, G.
    Li, H.
    CYTOTHERAPY, 2019, 21 (05) : S29 - S30
  • [37] Epicatechin attenuates doxorubicin-induced brain toxicity: Critical role of TNF-α, iNOS and NF-κB
    Mohamed, Rasha H.
    Karam, Rehab A.
    Amer, Mona G.
    BRAIN RESEARCH BULLETIN, 2011, 86 (1-2) : 22 - 28
  • [38] Rapid production of TNF-α following TCR engagement of naive CD8 T cells
    Brehm, MA
    Daniels, KA
    Welsh, RM
    JOURNAL OF IMMUNOLOGY, 2005, 175 (08): : 5043 - 5049
  • [39] The role of regulatory T cells in the Leishmania (Viannia) panamensis mouse model: a target for immunotherapy
    Ehrlich, Allison
    Castilho, Tiago
    Goldsmith-Pestana, Karen
    Sparwasser, Tim
    McMahon-Pratt, Diane
    JOURNAL OF IMMUNOLOGY, 2013, 190
  • [40] In Vitro Expansion of Highly Suppressive Xenoantigen-Specific Human Regulatory T Cells for Immunotherapy in Xenotransplantation
    Yi, S.
    Xi, J.
    Hawthorne, W. J.
    O'Connell, P. J.
    TRANSPLANTATION, 2012, 94 (10) : 781 - 781