Generation of immune checkpoint knock-out human antigen-specific T cells via CRISPR/Cas9-mediated genetic engineering

被引:0
|
作者
Zhang, C. [1 ]
Peng, Y. [1 ]
Hublitz, P. [1 ]
Dong, T. [1 ]
机构
[1] Univ Oxford, Weatherall Inst Mol Med WIMM, Nuffield Dept Med, Oxford, England
基金
英国医学研究理事会;
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
30
引用
收藏
页数:1
相关论文
共 50 条
  • [31] CRISPR/Cas9 mediated knock-out of VPREB1 gene induces a cytotoxic effect in myeloma cells
    Khaled, Mai
    Moustafa, Amr S.
    El-Khazragy, Nashwa
    Ahmed, Maha Imam
    Abd Elkhalek, Marwa Ali
    El-Salahy, Eman M.
    PLOS ONE, 2021, 16 (01):
  • [32] CRISPR/Cas9-mediated knock-in of a fluorescent reporter into the target locus of interest in human pluripotent stem cells
    Kim, A-Hyeon
    Lee, Ha Myoung
    Kim, Hong-Sik
    Jeong, Seong Woo
    Jun, Jong Kwan
    Jang, Jiho
    METHODSX, 2024, 13
  • [33] Generation of Knock-In Pigs Carrying Oct4-tdTomato Reporter through CRISPR/Cas9-Mediated Genome Engineering
    Lai, Sisi
    Wei, Shu
    Zhao, Bentian
    Ouyang, Zhen
    Zhang, Quanjun
    Fan, Nana
    Liu, Zhaoming
    Zhao, Yu
    Yan, Quanmei
    Zhou, Xiaoqing
    Li, Li
    Xin, Jige
    Zeng, Yangzhi
    Lai, Liangxue
    Zou, Qingjian
    PLOS ONE, 2016, 11 (01):
  • [34] Epigenetic profiles guide improved CRISPR/Cas9-mediated gene knockout in human T cells
    Ito, Yusuke
    Inoue, Satoshi
    Nakashima, Takahiro
    Zhang, Haosong
    Li, Yang
    Kasuya, Hitomi
    Matsukawa, Tetsuya
    Wu, Zhiwen
    Yoshikawa, Toshiaki
    Kataoka, Mirei
    Ishikawa, Tetsuo
    Kagoya, Yuki
    NUCLEIC ACIDS RESEARCH, 2024, 52 (01) : 141 - 153
  • [35] Effect of cryopreservation on A172 and U251 glioma cells infected with lentiviral vectors designed for CRISPR/Cas9-mediated aquaporin-8 knock-out
    Zhang, Hao
    Zhu, Shujuan
    Xing, Yu
    Liu, Qian
    Guo, Zhen
    Cai, Ziling
    Shen, Zihao
    Xia, Qingqian
    Sheng, Huajun
    PLOS ONE, 2022, 17 (03):
  • [36] Generation of three TTN knock-out human induced pluripotent stem cell lines using CRISPR/Cas9 system
    Kang, Ji -Young
    Mun, Dasom
    Chun, Yumin
    Park, Da -Seul
    Kim, Hyoeun
    Yun, Nuri
    Lee, Seung-Hyun
    Joung, Boyoung
    STEM CELL RESEARCH, 2022, 64
  • [37] Knock out of the annexin gene OsAnn3 via CRISPR/Cas9-mediated genome editing decreased cold tolerance in rice
    Shen, Chunxiu
    Que, Zhiqun
    Xia, Yumei
    Tang, Ning
    Li, Ding
    He, Ronghua
    Cao, Mengliang
    JOURNAL OF PLANT BIOLOGY, 2017, 60 (06) : 539 - 547
  • [38] Increasing Gene Editing Efficiency via CRISPR/Cas9- or Cas12a-Mediated Knock-In in Primary Human T Cells
    Kruglova, Natalia
    Shepelev, Mikhail
    BIOMEDICINES, 2024, 12 (01)
  • [39] Knock out of the annexin gene OsAnn3 via CRISPR/Cas9-mediated genome editing decreased cold tolerance in rice
    Chunxiu Shen
    Zhiqun Que
    Yumei Xia
    Ning Tang
    Ding Li
    Ronghua He
    Mengliang Cao
    Journal of Plant Biology, 2017, 60 : 539 - 547
  • [40] Curing genetic mutations for the next generation: CRISPR/Cas9-mediated gene correction in mouse spermatogonial stem cells
    Li, Dali
    SCIENCE BULLETIN, 2015, 60 (03) : 400 - 402