Aptamer Based Microfluidic Chip for Microbial Detection

Aptamer becomes a novel biosensor for detection of small chemical molecules, biological molecules, and cells. The integrating of aptamer biosensors with microfulidic chip for detection have attracted much attention due to their advantage of miniaturization, sensitivity and high specifity. Microbial detection is very important in the field of clinical diagnosis, environmental analysis and biodefense. It is highly desirable to develop a sensitive and rapid method for microbial detection. In this paper, we develop a novel method using aptamer based microfluidic chip for rapid and specific recognition of Lactobacillus acidophilus. It is will contribute to the microbial detection portably and rapidly.