Cell-in-Cell Phenomenon: A New Paradigm in Life Sciences

被引：11
|
作者：
Wang, X. [1 ]
机构：
[1] Chinese Peoples Liberat Army Gen Hosp, Key Lab Normal Aging & Geriatr, Inst Life Sci, Beijing 100853, Peoples R China
来源：
CURRENT MOLECULAR MEDICINE | 2015年 / 15卷 / 09期
基金：
中国国家自然科学基金;
关键词：
Cell-in-cell; cell-in-cell death; cell model; cell diversity; cell evolution; THYMIC NURSE CELLS; KILLER-CELLS; DEATH; EMPERIPOLESIS; CANNIBALISM; PHAGOCYTOSIS; CARCINOMA; ENTOSIS; DISEASE; LEADS;
D O I：
10.2174/1566524015666151026095730
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Cell-in-cell, a phenomenon characterized by one or more viable cells entering actively into another cell, was observed more than a century and has only attracted more attention in recent years and is becoming a new hot topic in the biological field, owing its biological significance in evolutionary as well as physiological and pathological relevance in development, homeostasis and diseases. In this paper we focus on the diversity, evolutionary conservatism and clinical implication of cell-in-cell as well as latest opinions on the research strategies. Based on the findings from our laboratory and other research groups three working models of cell-in-cell are also proposed.
引用
收藏
页码：810 / 818
页数：9
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