Inhibition of Integrin α5β1 With the Small Peptide Atn-161 Reduces Infarct Volume and Improves Functional Recovery Through Reduction of Blood-brain Barrier Permeability

被引:0
|
作者
Edwards, Danielle
Salmeron, Kathleen
Fraser, Justin F.
Bix, Gregory J.
机构
关键词
Stroke; Efficacy; Endothelial; Reperfusion injury; Infarct size;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
TMP28
引用
收藏
页数:2
相关论文
共 18 条
  • [11] Lnc00462717 regulates the permeability of the blood-brain tumor barrier through interaction with PTBP1 to inhibit the miR-186-5p/Occludin signaling pathway
    Zhang, Cai
    Zhang, Xiaoyi
    Wang, Jiahong
    Di, Fan
    Xue, Yixue
    Lin, Xiangdan
    Zhang, Ying
    Zhang, Hong
    Zhang, Zhou
    Gu, Yanting
    FASEB JOURNAL, 2020, 34 (08): : 9941 - 9958
  • [12] Glycogen Synthase Kinase 3β (GSK3β) Inhibition Prevents Monocyte (Mo) Migration Across the Blood-Brain Barrier (BBB) Via Suppression of Rac1-gtpase and Functional Activation of β-integrin
    Rom, S.
    Reichenbach, N. L.
    Fan, S.
    Dykstra, H.
    Ramirez, S.
    Persidsky, Y.
    JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2012, 7 : S52 - S53
  • [13] Bi-Functional Aspects of Peptide Decorated PLGA Nanocarriers for Enhanced Translocation Across the Blood-Brain Barrier through Macropinocytosis (Jun, 10.1007/s13233-022-0061-5, 2022)
    Vijayan, Ane Nishitha
    Indrakumar, Janani
    Gomathinayagam, Sankaranarayanan
    Gothandam, Kodiveri Muthukaliannan
    Korrapati, Purna Sai
    MACROMOLECULAR RESEARCH, 2022, 30 (08) : 597 - 597
  • [14] Pseudogene ACTBP2 increases blood-brain barrier permeability by promoting KHDRBS2 transcription through recruitment of KMT2D/WDR5 in Aβ1-42 microenvironment
    Liu, Qianshuo
    Liu, Xiaobai
    Zhao, Defeng
    Ruan, Xuelei
    Su, Rui
    Shang, Xiuli
    Wang, Di
    Yang, Chunqing
    Xue, Yixue
    CELL DEATH DISCOVERY, 2021, 7 (01)
  • [15] 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e), a novel calmodulin antagonist, reduces brain edema through the inhibition of enhanced blood-brain barrier permeability after transient focal ischemia
    Sato, T
    Morishima, Y
    Shirasaki, Y
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2003, 304 (03): : 1042 - 1047
  • [16] TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis
    Wu, Dongming
    Deng, Shihua
    Li, Li
    Liu, Teng
    Zhang, Ting
    Li, Jing
    Yu, Ye
    Xu, Ying
    CELL DEATH & DISEASE, 2021, 12 (08)
  • [17] Glial growth factor 2 treatment alleviates ischemia and reperfusion-damaged integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and Pdlim5/YAP/TAZ-mediated paracellular permeability
    Zhang, Xiao-ling
    Du, Wei-hong
    Qian, Shu-xia
    Lu, Xu-dong
    Yu, Xin
    Fang, Hai-lun
    Dong, Jia-li
    Song, Min
    Sun, Yan-yun
    Wu, Xiao-qiang
    Shen, Yu-fei
    Hao, Ya-nan
    Shen, Min-hui
    Zhou, Bei-qun
    Wang, Yan-ping
    Xu, Cong-ying
    Jin, Xin-chun
    ACTA PHARMACOLOGICA SINICA, 2024, 45 (11) : 2241 - 2252
  • [18] TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis (vol 12, 721, 2021)
    Wu, Dongming
    Deng, Shihua
    Li, Li
    Liu, Teng
    Zhang, Ting
    Li, Jing
    Yu, Ye
    Xu, Ying
    CELL DEATH & DISEASE, 2021, 12 (10)