Myxovirus Resistance Protein A Is a Useful Additional Histological Marker in Suspected Cutaneous Lupus Erythematosus

被引:3
|
作者
Lambers, Wietske M. [1 ]
Diercks, Gilles F. H. [2 ]
Homan, Femke M. [3 ]
Doornbos-van der Meer, Berber [1 ]
Bootsma, Hendrika [1 ]
Westra, Johanna [1 ]
de Leeuw, Karina [1 ]
机构
[1] Univ Groningen, Univ Med Ctr Groningen, Dept Rheumatol & Clin Immunol, Hanzepl 1, NL-9700 RB Groningen, Netherlands
[2] Univ Groningen, Univ Med Ctr Groningen, Dept Pathol, Hanzepl 1, NL-9700 RB Groningen, Netherlands
[3] Univ Groningen, Univ Med Ctr Groningen, Dept Dermatol, Hanzepl 1, NL-9700 RB Groningen, Netherlands
关键词
EXPRESSION;
D O I
10.2340/00015555-3587
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Cutaneous lupus erythematosus (CLE) is a heterogeneous autoimmune skin disease. Since the clinical picture can be quite heterogeneous, histological confirmation is of importance. However, the typical histological features, including an interface dermatitis, are not at all specific. As CLE is an interferon (IFN)-driven disease, IFN-related markers, such as myxovirus resistance protein A (MxA), could be helpful in the diagnostic process. This can be illustrated by 2 cases.
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页数:2
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