A RESAMPLING-BASED TEST TO DETECT PERSON-TO-PERSON TRANSMISSION OF INFECTIOUS DISEASE

被引：6

作者：

Yang, Yang ^{[1
]}

Longini, Ira M., Jr. ^{[1
]}

Halloran, M. Elizabeth ^{[1
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Program Biostat & Biomath, Seattle, WA 98109 USA

来源：

ANNALS OF APPLIED STATISTICS | 2007年 / 1卷 / 01期

关键词：

Resampling; permutation; hypothesis test; infectious disease; transmission; likelihood ratio; MLE;

D O I：

10.1214/07-AOAS105

中图分类号：

O21 [概率论与数理统计]; C8 [统计学];

学科分类号：

020208 ; 070103 ; 0714 ;

摘要：

Early detection of person-to-person transmission of emerging infectious diseases Such as avian influenza is crucial for containing pandemies. We developed a simple permutation test and its refined version for this purpose. A Simulation Study shows that the refined permutation test is its powerful as or outcompetes the conventional test built on asymptotic theory. especially when the sample size is small. In addition, Our resampling methods can be applied to a broad range of problems where an asymptotic test is not available or fails. we also found that decent statistical power could be attained with just a small number of cases, if the disease is moderately transmissible between humans.

引用

页码：211 / 228

页数：18

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