Synthesis and antimicrobial properties of S-substituted derivatives of 4-thiouracil

被引:0
|
作者
Wyrzykiewicz, E [1 ]
Nowakowska, Z [1 ]
Bartkowiak, G [1 ]
Kedzia, B [1 ]
机构
[1] INST MED PLANTS,POZNAN,POLAND
关键词
4-thiouracil; 4-azachalcone; 4-alkylthiouracils; (E)-N-uracilthioalkyl]-substituted 4-azachalconium bromides; antimicrobial activity;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The synthesis of 16 new 4-alkylthio- and 4-(E)-N-thioalkyl-4-azachalconyl substituted derivatives of uracil and their antimicrobial activity are reported. Compounds 5a and 5c showed a goad antimicrobial activity against Staphylococcus aureus and a moderate activity against Streptococcus feacalis.
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页码:201 / 206
页数:6
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