LOSS OF AMPLIFIED EGFR GENE WITH MUTATION AS A NOVEL MECHANISM OF ACQUIRED RESISTANCE TO EGFR-TKIS IN EGFR MUTATED NSCLC CELLS

被引：0
|
作者：
Furugaki, K. [1 ]
Iwai, T. [1 ]
Moriya, Y. [1 ]
Fujimoto-Ouchi, K. [2 ]
机构：
[1] Chugai Pharmaceut Co Ltd, Prod Res Dept, Kamakura, Kanagawa, Japan
[2] Chugai Pharmaceut Co Ltd, Discovery Pharmacol Dept, Kamakura, Kanagawa, Japan
来源：
ANNALS OF ONCOLOGY | 2012年 / 23卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：390 / 391
页数：2
相关论文
共 50 条
  • [11] Bisphosphonates enhance effect of EGFR-TKIs in NSCLC patients with EGFR mutation and bone metastases
    Jiang, T.
    Zhou, C.
    ANNALS OF ONCOLOGY, 2016, 27
  • [12] Bisphosphonates Enhance Effect of EGFR-TKIs in NSCLC Patients with EGFR Mutation and Bone Metastases
    Jiang, Tao
    Zhou, Caicun
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (01) : S1236 - S1236
  • [13] Combination of EGFR-TKIs and chemotherapy in advanced EGFR mutated NSCLC: Review of the literature and future perspectives
    Rebuzzi, Sara Elena
    Alfieri, Roberta
    La Monica, Silvia
    Minari, Roberta
    Petronini, Pier Giorgio
    Tiseo, Marcello
    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2020, 146
  • [14] Efficacy of 3rd Generation EGFR-TKIs After Failing First or Second Generation EGFR-TKIs in EGFR Mutation-Positive NSCLC (ROOT-EGFR)
    Jung, H. A.
    Hong, S.
    Park, J.
    Park, M. R.
    Sun, J.
    Lee, S.
    Ahn, J. S.
    Ahn, M.
    Park, K.
    JOURNAL OF THORACIC ONCOLOGY, 2019, 14 (10) : S853 - S853
  • [15] THE CONCOMITANT GENE ALTERATIONS IMPACT THE THERAPEUTIC EFFICACY OF EGFR-TKIS IN ADVANCED NSCLC PATIENTS WITH EGFR SENSITIVE MUTATION
    Chang, Cheng-Yu
    Chang, Shih-Chieh
    Lai, Jiun-I
    Lai, Yi-Chun
    RESPIROLOGY, 2019, 24 : 272 - 272
  • [16] Epithelial to mesenchymal transition in acquired resistance to EGFR-TKIs
    Rho, Jin Kyung
    Chung, Jin-Haeng
    Sung, Sook-Whan
    Lee, Jong Seok
    Yoon, Ho Il
    Choi, Yun Jung
    Kim, Cheol Hyeon
    Lee, Jae Cheol
    CANCER RESEARCH, 2009, 69
  • [17] Dynamic Evaluation of Circulating miRNA Profile in EGFR-Mutated NSCLC Patients Treated with EGFR-TKIs
    Leonetti, Alessandro
    Capula, Mjriam
    Minari, Roberta
    Mazzaschi, Giulia
    Gregori, Alessandro
    El Hassouni, Btissame
    Papini, Filippo
    Bordi, Paola
    Verze, Michela
    Avan, Amir
    Tiseo, Marcello
    Giovannetti, Elisa
    CELLS, 2021, 10 (06)
  • [18] Tamoxifen Might Enhance the Effect of EGFR-TKIs on EGFR-Mutant NSCLC Cells
    He, Y.
    Zhang, Q.
    Zheng, M.
    Chen, Z.
    Wei, X.
    Yang, X.
    Gao, X.
    Wu, Y.
    Liu, S.
    Zhou, Q.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (03) : S242 - S242
  • [19] Microwave ablation combined with EGFR-TKIs versus only EGFR-TKIs in advanced NSCLC patients with EGFR-sensitive mutations
    Wei, Zhigang
    Ye, Xin
    Yang, Xia
    Zheng, Aimin
    Huang, Guanghui
    Li, Wenhong
    Wang, Jiao
    Han, Xiaoying
    Meng, Min
    Ni, Yang
    ONCOTARGET, 2017, 8 (34) : 56714 - 56725
  • [20] ANALYSIS OF SENSITIVITY OF LUNG SQUAMOUS CARCINOMA WITH EGFR MUTATION TO EGFR-TKIS AND RESISTANT MECHANISM
    Wang, Zhijie
    Li, Zhenxiang
    Yang, Xiaodan
    Bai, Hua
    Zhuo, Minglei
    Duan, Jianchun
    Wang, Jie
    JOURNAL OF THORACIC ONCOLOGY, 2013, 8 : S798 - S798
12345