Mutations in DMC1 are not responsible for premature ovarian failure in Chinese women

被引：8
|
作者：
Wang, Huidan [1 ]
Sun, Mei [1 ]
Qin, Yingying [1 ]
Xia, Tingting [2 ]
Ma, Jinlong [1 ]
Chen, Zi-Jiang [1 ]
机构：
[1] Shandong Univ, Prov Hosp,Key Lab Reprod Endocrinol, Minist Educ,Ctr Reprod Med,Shandong Prov Key Lab, Natl Res Ctr Assisted Reprod Technol & Reprod Gen, Jinan 250021, Peoples R China
[2] Sun Yat Sen Univ Med Sci, Affiliated Hosp 1, Guangzhou 510080, Guangdong, Peoples R China
来源：
REPRODUCTIVE BIOMEDICINE ONLINE | 2013年 / 26卷 / 02期
基金：
中国国家自然科学基金;
关键词：
DMC1; mutation; premature ovarian failure; single-nucleotide polymorphism; FOLLICLE-STIMULATING-HORMONE; CHROMOSOME SYNAPSIS; BETA-SUBUNIT; RECEPTOR; GENE; INSUFFICIENCY; EXPRESSION; RESISTANCE; MEIOSIS; HOMOLOG;
D O I：
10.1016/j.rbmo.2012.10.016
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
The coding region of the disrupted meiotic cDNA gene (DMC1) was examined in 192 Chinese women with premature ovarian failure. Two known single-nucleotide polymorphisms, c.8632C>T in intron 4 and c.32377G>C in intron 10, were identified. The results suggest that mutations in the coding sequence of DMC1 are not associated with premature ovarian failure in Chinese women. RBMOnline (C) 2012, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：175 / 178
页数：4
相关论文
共 50 条
  • [31] Quality of life in women with premature ovarian failure
    Benetti-Pinto, Cristina L.
    de Almeida, Deborah M. B.
    Makuch, Maria Y.
    GYNECOLOGICAL ENDOCRINOLOGY, 2011, 27 (09) : 645 - 649
  • [32] A study of premature ovarian failure in Turkish women
    Gokmen, O
    Seckin, NC
    Sener, AB
    Ozaksit, G
    Ekmekci, S
    GYNECOLOGICAL ENDOCRINOLOGY, 1995, 9 (04) : 283 - 287
  • [33] A pathogenic DMC1 frameshift mutation causes nonobstructive azoospermia but not primary ovarian insufficiency in humans
    Cao, Dandan
    Shi, Fu
    Guo, Chenxi
    Liu, Ye
    Lin, Zexiong
    Zhang, Juanhui
    Li, Raymond Hang Wun
    Yao, Yuanqing
    Liu, Kui
    Ng, Ernest Hung Yu
    Yeung, William Shu Biu
    Wang, Tianren
    MOLECULAR HUMAN REPRODUCTION, 2021, 27 (09)
  • [34] Circulating markers of autoimmunity in Chinese women with premature ovarian failure and age-matched healthy women
    Zhen, X.
    Qiao, J.
    Li, R.
    Wang, L.
    Liu, P.
    HUMAN REPRODUCTION, 2011, 26 : I108 - I108
  • [35] Dissecting 2 Meiotic Mutations (dmc1 and asy1) in Artificial Autopolyploid Arabidopsis thaliana
    Tian, Bao-ming
    Yan, Biao
    Gao, Jin-yan
    Si, Yan-hong
    Zang, Xin
    CYTOLOGIA, 2011, 76 (04) : 411 - 423
  • [36] DETECTION OF ANTIBODIES TO OVARIAN ANTIGENS IN WOMEN WITH PREMATURE OVARIAN FAILURE
    WHEATCROFT, NJ
    TOOGOOD, AA
    LI, TC
    COOKE, ID
    WEETMAN, AP
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 1994, 96 (01): : 122 - 128
  • [37] Screening for FOXL2 gene mutations in women with premature ovarian failure:: an Indian experience
    Chatterjee, Supama
    REPRODUCTIVE BIOMEDICINE ONLINE, 2007, 15 (05) : 554 - 560
  • [38] FAILURE TO IDENTIFY HETEROZYGOTES FOR GALACTOSEMIA IN WOMEN WITH PREMATURE OVARIAN FAILURE
    FRASER, IS
    SHEARMAN, RP
    WILCKEN, B
    BROWN, A
    DAVIS, K
    LANCET, 1987, 2 (8558): : 566 - 566
  • [39] Mutations in FIGLA Associated With Premature Ovarian Insufficiency in a Chinese Population
    Mei, Libin
    Huang, Yanru
    Wu, Xiaoling
    He, Huang
    Ye, Ronghui
    Ma, Jinxiu
    He, XueMei
    Shi, Yuhua
    Li, Ping
    FRONTIERS IN MEDICINE, 2021, 8
  • [40] Mutation analysis of the WNT4 gene in Han Chinese women with premature ovarian failure
    Chen, Beili
    Suo, Peisu
    Wang, Binbin
    Wang, Jing
    Yang, Lu
    Zhou, Sirui
    Zhu, Ying
    Ma, Xu
    Cao, Yunxia
    REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 2011, 9
12345