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Enhanced chemiluminescence of the luminol-hydrogen peroxide system by BSA-stabilized Au nanoclusters as a peroxidase mimic and its application
被引:65
|作者:
Deng, Mao
[1
]
Xu, Shuangjiao
[1
]
Chen, Funan
[1
]
机构:
[1] Southwest Univ, Sch Chem & Chem Engn, Minist Educ, Key Lab Luminescence & Real time Anal, Chongqing 400715, Peoples R China
关键词:
LIQUID-CHROMATOGRAPHY;
GOLD NANOPARTICLES;
DIRECTED SYNTHESIS;
LUMINESCENCE;
IMMUNOASSAY;
SENSORS;
ASSAY;
D O I:
10.1039/c3ay42135j
中图分类号:
O65 [分析化学];
学科分类号:
070302 ;
081704 ;
摘要:
In the present work, water-soluble Au nanoclusters capped with bovine serum albumin (BSA) were synthesized. It was found that as a peroxidase mimic, Au nanoclusters could enhance the chemiluminescence (CL) emission from the luminol-hydrogen peroxide system in alkaline medium, and the enhancement mechanism of the Au nanoclusters on luminol CL is discussed. The effects were also investigated of the concentration of the reactants and some organic compounds The proposed method could be used as a sensitive detection tool for hydrogen peroxide and glucose.
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页码:3117 / 3123
页数:7
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