Anti-Idiotypic Monoclonal Antibodies Targeting the Germline Variant of a Broadly Neutralizing HIV-Specific Antibody VRC01

被引:0
|
作者
Gorchakov, Andrey A. [1 ,2 ]
Volkova, Olga Y. [1 ]
Baranov, Konstantin O. [1 ]
Chernikova, Daria S. [1 ,2 ]
Mechetina, Lyudmila V. [1 ]
Belovezhets, Tatyana N. [1 ,2 ]
Chikaev, Nikolay A. [1 ]
Kulemzin, Sergey V. [1 ]
Taranin, Alexandr V. [1 ,2 ]
机构
[1] Inst Mol Cellular Biol, Novosibirsk, Russia
[2] Novosibirsk State Univ, Novosibirsk, Russia
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
298
引用
收藏
页码:143 / 144
页数:2
相关论文
共 50 条
  • [21] Characterization of VRC01, a potent and broadly neutralizing anti-HIV mAb, produced in transiently and stably transformed tobacco
    Teh, Audrey Y-H.
    Maresch, Daniel
    Klein, Katja
    Ma, Julian K-C.
    PLANT BIOTECHNOLOGY JOURNAL, 2014, 12 (03) : 300 - 311
  • [22] Modeling HIV-1 Within-Host Dynamics After Passive Infusion of the Broadly Neutralizing Antibody VRC01
    Cardozo-Ojeda, E. Fabian
    Perelson, Alan S.
    FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [23] Randomized Clinical Trial to Assess the Impact of the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01 on HIV-1 Persistence in Individuals on Effective ART
    Riddler, Sharon A.
    Zheng, Lu
    Durand, Christine M.
    Ritz, Justin
    Koup, Richard A.
    Ledgerwood, Julie
    Bailer, Robert T.
    Koletar, Susan L.
    Eron, Joseph J.
    Keefer, Michael C.
    Macatangay, Bernard J. C.
    Cyktor, Joshua C.
    Mellors, John W.
    OPEN FORUM INFECTIOUS DISEASES, 2018, 5 (10):
  • [24] HIV-specific broadly neutralizing monoclonal antibody, VRC01, minimally impacts time to viral rebound following treatment interruption in virologically suppressed, HIV-infected participants who initiated antiretroviral therapy during acute HIV infection
    Crowell, T. A.
    Colby, D. J.
    Pinyakorn, S.
    Intasan, J.
    Benjapornpong, K.
    Tanjnareel, K.
    Chomont, N.
    Trautmann, L.
    Tovanabutra, S.
    Krebs, S.
    Bolton, D.
    McDermott, A.
    Bailer, R.
    Doria-Rose, N.
    Patel, B.
    Gorelick, R. J.
    Fullmer, B. A.
    Visudhiphan, P.
    O'Connell, R. J.
    Tressler, R.
    Mascola, J.
    Michael, N. L.
    Robb, M. L.
    Phanuphak, N.
    Ananworanich, J.
    JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2017, 20 : 111 - 112
  • [25] Topical gel formulation of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 confers protection against HIV-1 vaginal challenge in a humanized mouse model
    Veselinovic, Milena
    Neff, C. Preston
    Mulder, Leila R.
    Akkina, Ramesh
    VIROLOGY, 2012, 432 (02) : 505 - 510
  • [26] Peptides imitating the epitope of a broadly HIV-neutralizing antibody VRC01 are capable of stimulating human sensor B cell lines
    Chikaev, A.
    Rudometov, A.
    Mechetina, L.
    Belovezhets, T.
    Ilyichev, A.
    Taranin, A.
    Karpenko, L.
    JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2021, 24
  • [27] Selection of Peptide Mimics of HIV-1 Epitope Recognized by Neutralizing Antibody VRC01
    Chikaev, Anton N.
    Bakulina, Anastasiya Yu.
    Burdick, Ryan C.
    Karpenko, Larisa I.
    Pathak, Vinay K.
    Ilyichev, Alexander A.
    PLOS ONE, 2015, 10 (03):
  • [28] Retention in the Ongoing AMP Trials of VRC01, a Broadly Neutralizing Antibody (bnAb) to Prevent HIV in Women, MSM & Transgender (TG) People
    Andrew, Philip
    Andrasik, Michele
    Thommes, Erika
    deCamp, Allan
    Kochar, Nidhi
    Karg, Carissa
    Greene, Elizabeth
    Tindale, India
    Lucas, Jonathan
    Broder, Gail
    Wallace, Stephaun
    Oseso, Linda
    Lorenzo, Margarita Gomez
    Burns, David
    Edupuganti, Srilatha
    Mgodi, Nyaradzo
    Cohen, Myron
    Corey, Larry
    Karuna, Shelly
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2018, 34 : 186 - 186
  • [29] A Single Residue within the V5 Region of HIV-1 Envelope Facilitates Viral Escape from the Broadly Neutralizing Monoclonal Antibody VRC01
    Guo, Dongxing
    Shi, Xuanling
    Arledge, Kelly C.
    Song, Dingka
    Jiang, Liwei
    Fu, Lili
    Gong, Xinqi
    Zhang, Senyan
    Wang, Xinquan
    Zhang, Linqi
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (51) : 43170 - 43179
  • [30] Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization
    Parks, K. Rachael
    MacCamy, Anna J.
    Trichka, Josephine
    Gray, Matthew
    Weidle, Connor
    Borst, Andrew J.
    Khechaduri, Arineh
    Takushi, Brittany
    Agrawal, Parul
    Guenaga, Javier
    Wyatt, Richard T.
    Coler, Rhea
    Seaman, Michael
    LaBranche, Celia
    Montefiori, David C.
    Veesler, David
    Pancera, Marie
    McGuire, Andrew
    Stamatatos, Leonidas
    CELL REPORTS, 2019, 29 (10): : 3060 - +