Depression is linked to deficits in cognitive control and a host of other cognitive impairments arise as a consequence of these deficits. Despite of their important role in depression, there are no mechanistic models of cognitive control deficits in depression. In this paper we propose how these deficits can emerge from the interaction between motivational and cognitive processes. We review depression-related impairments in key components of motivation along with new cognitive neuroscience models that focus on the role of motivation in the decision-making about cognitive control allocation. Based on this review we propose a unifying framework which connects motivational and cognitive control deficits in depression. This framework is rooted in computational models of cognitive control and offers a mechanistic understanding of cognitive control deficits in depression.
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Spectrum CBT, Los Angeles, CA USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Liao, Allen
Walker, Robrina
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Univ Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Walker, Robrina
Carmody, Thomas J.
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Univ Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Carmody, Thomas J.
Cooper, Crystal
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Univ Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Cooper, Crystal
Shaw, Meredith A.
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VA North Texas Hlth Care Syst, Dallas, TX USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Shaw, Meredith A.
Grannemann, Bruce D.
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Univ Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Grannemann, Bruce D.
Adams, Phil
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Columbia Univ, Dept Psychiat, New York, NY 10027 USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Adams, Phil
Bruder, Gerard E.
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Columbia Univ, Dept Psychiat, New York, NY 10027 USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Bruder, Gerard E.
McInnis, Melvin G.
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Univ Michigan, Dept Psychiat, Ann Arbor, MI 48109 USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
McInnis, Melvin G.
Webb, Christian A.
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Harvard Med Sch, Dept Psychiat, Boston, MA USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Webb, Christian A.
Dillon, Daniel G.
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Harvard Med Sch, Dept Psychiat, Boston, MA USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Dillon, Daniel G.
Pizzagalli, Diego A.
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Harvard Med Sch, Dept Psychiat, Boston, MA USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Pizzagalli, Diego A.
Phillips, Mary L.
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Univ Pittsburgh, Med Ctr, Pittsburgh, PA 15260 USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Phillips, Mary L.
Kurian, Benji T.
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Univ Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Kurian, Benji T.
Fava, Maurizio
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Harvard Med Sch, Dept Psychiat, Boston, MA USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Fava, Maurizio
Parsey, Ramin V.
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SUNY Stony Brook, Dept Psychiat, Sch Med, Stony Brook, NY 11794 USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Parsey, Ramin V.
McGrath, Patrick J.
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机构:
Columbia Univ, Dept Psychiat, New York, NY 10027 USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
McGrath, Patrick J.
Weissman, Myrna M.
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Columbia Univ, Mailman Sch Publ Hlth, New York, NY 10027 USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
Weissman, Myrna M.
Trivedi, Madhukar H.
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机构:
Univ Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USAUniv Texas Southwestern Med Ctr Dallas, Dept Psychiat, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USA