Seasonal Distribution of Psychiatric Births in England

被引：43
|
作者：
Disanto, Giulio [1 ,2 ]
Morahan, Julia M. [1 ,2 ]
Lacey, Melanie V. [3 ]
DeLuca, Gabriele C. [1 ,2 ]
Giovannoni, Gavin [4 ]
Ebers, George C. [1 ,2 ]
Ramagopalan, Sreeram V. [1 ,2 ,3 ,4 ]
机构：
[1] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England
[2] Univ Oxford, Dept Clin Neurol, Oxford, England
[3] London Sch Hyg & Trop Med, London WC1, England
[4] Queen Mary Univ London, Barts & London Sch Med & Dent, Blizard Inst Cell & Mol Sci, London, England
来源：
PLOS ONE | 2012年 / 7卷 / 04期
基金：
英国惠康基金; 英国医学研究理事会;
关键词：
BIPOLAR DISORDER; NORTHERN-HEMISPHERE; ADULT DISEASE; SCHIZOPHRENIA; RISK; POPULATION; SIBLINGS; SUICIDE; ORIGINS;
D O I：
10.1371/journal.pone.0034866
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
There is general consensus that season of birth influences the risk of developing psychiatric conditions later in life. We aimed to investigate whether the risk of schizophrenia (SC), bipolar affective disorder (BAD) and recurrent depressive disorder (RDD) is influenced by month of birth in England to a similar extent as other countries using the largest cohort of English patients collected to date (n = 57,971). When cases were compared to the general English population (n = 29,183,034) all diseases showed a seasonal distribution of births (SC p = 2.48E-05; BAD p = 0.019; RDD p = 0.015). This data has implications for future strategies of disease prevention.
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页数：4
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