Allosteric regulation of the ligand-binding ability of Zn-porphyrin by metal complexation

被引：5

作者：

Kozaki, Masatoshi ^{[1
]}

Ninomiya, Yoshikazu ^{[1
]}

Suzuki, Shuichi ^{[1
]}

Okada, Keiji ^{[1
]}

机构：

[1] Osaka City Univ, Grad Sch Sci, Sumiyoshi Ku, Osaka 5588585, Japan

来源：

TETRAHEDRON LETTERS | 2013年 / 54卷 / 28期

关键词：

Allosteric system; Porphyrin; Bipyridine; Axial ligand; Sonogashira coupling; SYSTEMS; PSEUDOCRYPTAND; CASCADE;

D O I：

10.1016/j.tetlet.2013.04.130

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Zn-porphyrin with bipyridyl units at the ends of a conjugated chain, in addition to two alkyl side chains, was prepared as an artificial allosteric system. The axial ligand-binding ability of the compound was considerably reduced by the formation of a Fe(bpy)(3)-type complex. The degree of the allosteric suppression strongly depended on both alkyl chain length and the steric demand of the pyridyl ligand. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：3658 / 3661

页数：4

共 50 条

[1] Allosteric Regulation of the Ligand-Binding Ability of Zinc Porphyrins with Sterically Bulky Shielding Units by Metal Complexation
Ninomiya, Yoshikazu
Kozaki, Masatoshi
Suzuki, Shuichi
Okada, Keiji
[J]. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 2014, 87 (11) : 1195 - 1201
[2] ALLOSTERIC LIGAND-BINDING TO COFACIAL METALLOPORPHYRIN DIMERS - THE MECHANISM OF PORPHYRIN DISAGGREGATION
HUNTER, CA
LEIGHTON, P
SANDERS, JKM
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1989, (03): : 547 - 552
[3] LIGAND-BINDING IN PORPHYRIN SYSTEMS
GALLAGHER, WA
ELLIOTT, WB
[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1973, 206 (OCT22) : 463 - 482
[4] REGULATION OF RETINOID SIGNALING BY RECEPTOR POLARITY AND ALLOSTERIC CONTROL OF LIGAND-BINDING
KUROKAWA, R
DIRENZO, J
BOEHM, M
SUGARMAN, J
GLOSS, B
ROSENFELD, MG
HEYMAN, RA
GLASS, CK
[J]. NATURE, 1994, 371 (6497) : 528 - 531
[5] Ligand-Binding Ability of a Porphyrin Core in a Dendrimer with Rigid Branched Terminal Components
Akisada, Mami
Kimura, Ryo
Tachi, Yoshimitsu
Suzuki, Shuichi
Okada, Keiji
Kozaki, Masatoshi
[J]. JOURNAL OF ORGANIC CHEMISTRY, 2018, 83 (17): : 9631 - 9640
[6] ALLOSTERIC TRANSITION AND LIGAND-BINDING IN HEMOGLOBIN CHESAPEAKE
GIBSON, QH
NAGEL, RL
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1974, 249 (22) : 7255 - 7259
[7] Synthesis and properties of Zn-porphyrin with bipyridine-terminated side chains: large conformational change induced by metal complexation
Kato, Mutsumi
Hashimoto, Erika
Kozaki, Masatoshi
Suzuki, Shuichi
Okada, Keiji
[J]. TETRAHEDRON LETTERS, 2012, 53 (03) : 309 - 312
[8] LIGAND-BINDING TO MACROMOLECULES - ALLOSTERIC AND SEQUENTIAL MODELS OF COOPERATIVITY
HESS, VL
SZABO, A
[J]. JOURNAL OF CHEMICAL EDUCATION, 1979, 56 (05) : 289 - 293
[9] Synthesis and Catalytic Study of Ruthenium Carbene Catalyst Containing a Zn-Porphyrin Ligand
Xu, Ying
Zhang, Huizhu
Wang, Xinyuan
Liu, Guiyan
[J]. CHINESE JOURNAL OF CHEMISTRY, 2015, 33 (12) : 1393 - 1397
[10] Surface modification of zinc oxide nanorods with Zn-porphyrin via metal-ligand coordination for photovoltaic applications
Park, Juhyun
Lee, Yebin
Kim, Jungtae
[J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244

← 1 2 3 4 5 →